Western Blot (WB)
(Western Blot of MBS540046 with rat brain cortical membranes. 1:250 antibody dilution in DiluObuffer. Apparent MW is 80 kDa.)
Rabbit Norepinephrine Transporter Polyclonal Antibody | anti-SLC6A2 antibody
Norepinephrine Transporter Antibody
Dot Blot: 1:4,000
ELISA: 1:4,000
Immunocytochemistry: 1:100
Immunofluorescence: 1:100
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:250
Western Blot (WB)
(Western Blot of MBS540046 with rat brain cortical membranes. 1:250 antibody dilution in DiluObuffer. Apparent MW is 80 kDa.)
Western Blot (WB)
(Western Blot of MBS540046 with rat brain cortical membranes. 1:250 antibody dilution in DiluObuffer. Apparent MW is 80 kDa.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Uniprot Description
SLC6A2: Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals. Defects in SLC6A2 are a cause of orthostatic intolerance (OI). OI is a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. It is associated with postural tachycardia. Plasma norepinephrine concentration is abnormally high. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily.
Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 16q12.2
Cellular Component: integral to plasma membrane; membrane; neuron projection; plasma membrane
Molecular Function: dopamine:sodium symporter activity; metal ion binding; monoamine transmembrane transporter activity; norephinephrine:sodium symporter activity; protein binding
Biological Process: dopamine uptake; monoamine transport; norepinephrine transport; response to pain; synaptic transmission; transmembrane transport; transport
Disease: Orthostatic Intolerance
Research Articles on SLC6A2
Similar Products
Product Notes
The SLC6A2 slc6a2 (Catalog #AAA540046) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Norepinephrine Transporter Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Norepinephrine Transporter can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Confocal Microscopy: 1:100 Dot Blot: 1:4,000 ELISA: 1:4,000 Immunocytochemistry: 1:100 Immunofluorescence: 1:100 Immunohistochemistry: 1:100 Immunoprecipitation: 1:200 Western Blot: 1:250. Researchers should empirically determine the suitability of the SLC6A2 slc6a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Norepinephrine Transporter, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
