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Western Blot (WB) (Western Blot analysis of NOP58 in K562, 231, Hela, HepG2, A172, 293T cell lysates in order using NOP58 Rabbit pAb at dilution 1/600)

Rabbit NOP58 Polyclonal Antibody | anti-NOP58 antibody

NOP58 Rabbit pAb

Gene Names
NOP58; NOP5; HSPC120; NOP5/NOP58
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
NOP58; Polyclonal Antibody; NOP58 Rabbit pAb; NOP58 ribonucleoprotein; NOP5; HSPC120; NOP5/NOP58; anti-NOP58 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.6mg/ml (varies by lot)
Applicable Applications for anti-NOP58 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:50-1:200
Immunogen
Fusion protein of human NOP58
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of NOP58 in K562, 231, Hela, HepG2, A172, 293T cell lysates in order using NOP58 Rabbit pAb at dilution 1/600)

Western Blot (WB) (Western Blot analysis of NOP58 in K562, 231, Hela, HepG2, A172, 293T cell lysates in order using NOP58 Rabbit pAb at dilution 1/600)

Immunohistochemistry (IHC)

(Immunohistochemistry of NOP58 in paraffin-embedded Human breast cancer tissue using NOP58 Rabbit pAb at dilution 1/85. Predicted cell location: Nucleus)

Immunohistochemistry (IHC) (Immunohistochemistry of NOP58 in paraffin-embedded Human breast cancer tissue using NOP58 Rabbit pAb at dilution 1/85. Predicted cell location: Nucleus)
Related Product Information for anti-NOP58 antibody
The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
529
NCBI Official Full Name
Nucleolar protein 58
NCBI Official Synonym Full Names
NOP58 ribonucleoprotein
NCBI Official Symbol
NOP58
NCBI Official Synonym Symbols
NOP5; HSPC120; NOP5/NOP58
NCBI Protein Information
nucleolar protein 58; nucleolar protein NOP5/NOP58; NOP58 ribonucleoprotein homolog
UniProt Protein Name
Nucleolar protein 58
Protein Family
UniProt Gene Name
NOP58
UniProt Synonym Gene Names
NOL5; NOP5
UniProt Entry Name
NOP58_HUMAN

Uniprot Description

NOP5: Required for 60S ribosomal subunit biogenesis. Belongs to the NOP5/NOP56 family.

Protein type: Nucleolus; Cell development/differentiation; RNA-binding

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: Cajal body; small nucleolar ribonucleoprotein complex; membrane; cytoplasm; nucleolus; nucleus

Molecular Function: snoRNA binding; protein binding

Biological Process: rRNA modification; snRNP protein import into nucleus; cell growth; rRNA processing

Research Articles on NOP58

Similar Products

Product Notes

The NOP58 nop58 (Catalog #AAA4760552) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOP58 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NOP58 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the NOP58 nop58 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOP58, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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