Rabbit Non-structural glycoprotein 4 Polyclonal Antibody | anti-NSP4 antibody

Rabbit anti-Rotavirus A (strain RVA/Cow/United States/NCDV-Lincoln/1969/G6P6[1])(RV-A)(Rotavirus A (strain Nebraska calf diarrhea virus)) Non-structural glycoprotein 4 Polyclonal Antibody

• Reactivity: Rotavirus A (strain RVA/Cow/United States/NCDV-Lincoln/1969/G6P6[1])(RV-A)(Rotavirus A (strain Nebraska calf diarrhea virus))
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: Non-structural glycoprotein 4; Polyclonal Antibody; Rabbit anti-Rotavirus A (strain RVA/Cow/United States/NCDV-Lincoln/1969/G6P6[1])(RV-A)(Rotavirus A (strain Nebraska calf diarrhea virus)) Non-structural glycoprotein 4 Polyclonal Antibody; Non-structural glycoprotein 4 Antibody; NSP4; NCVP5; NS28; anti-NSP4 antibody

• Host: Rabbit
• Reactivity: Rotavirus A (strain RVA/Cow/United States/NCDV-Lincoln/1969/G6P6[1])(RV-A)(Rotavirus A (strain Nebraska calf diarrhea virus))
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-NSP4 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Rotavirus A Non-structural glycoprotein 4 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 139542
• UniProt Accession #: P08434
• Molecular Weight: 20.9 kDa
• NCBI Official Full Name: Non-structural glycoprotein 4
• UniProt Protein Name: Non-structural glycoprotein 4
• Protein Family: Nitrile-specifier protein
• UniProt Gene Name: NSP4
• UniProt Synonym Gene Names: NSP4
• UniProt Entry Name: NSP4_ROTBN

Uniprot Description

Involved in virus morphogenesis. Functions as a receptor for the immature double-layered inner capsid particle (ICP) which transiently buds into the lumen of the rough endoplasmic reticulum during viral maturation.Enterotoxin that causes a phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells. Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability. Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea. To perform this enterotoxigenic role in vivo, NSP4 is probably released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with the plasma membrane receptors on neighboring epithelial cells. Possible receptors for NSP4 are alpha-1/beta-1 and alpha-2/beta-1 integrin heterodimers ().