Western Blot (WB)
(Western blot analysis of NOM1 expression in HEK293T (A), H9C2 (B) whole cell lysates.)
Rabbit anti-Human, Rat NOM1 Polyclonal Antibody | anti-NOM1 antibody
Anti-NOM1 Antibody
Western Blot (WB)
(Western blot analysis of NOM1 expression in HEK293T (A), H9C2 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of NOM1 expression in HEK293T (A), H9C2 (B) whole cell lysates.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of NOM1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of NOM1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
NCBI and Uniprot Product Information
NCBI Description
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]
Uniprot Description
NOM1: a nucleolar protein that binds eIF4A and encoded within the chromosome 7q36 breakpoint region associated with pediatric acute myeloid leukemia. Contains an MIF4G and an MA3 domain. MIF4G and MA3 domains bind proteins of the eIF4A family of ATP-dependent DEAD-box RNA helicases required for both translation and nonsense-mediated decay. MIF4G domains are found in several proteins involved in RNA metabolism, including eIF4G, eIF-2b, UPF2, and nuclear cap-binding proteins.
Protein type: Nucleolus; Unknown function
Chromosomal Location of Human Ortholog: 7q36.3
Cellular Component: nucleolus; nucleus
Molecular Function: protein binding
Research Articles on NOM1
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Product Notes
The NOM1 nom1 (Catalog #AAA8215871) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NOM1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NOM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB (1/500 - 1/1000), IHC (1/100 - 1/200). Researchers should empirically determine the suitability of the NOM1 nom1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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