Rabbit NMT1 Polyclonal Antibody | anti-NMT1 antibody

NMT1 Polyclonal Antibody

Cat. Num. AAA2523807

• Gene Names: NMT1; NMT
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: NMT1; Polyclonal Antibody; NMT1 Polyclonal Antibody; NMT; anti-NMT1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 2.8mg/mL (varies by lot)
• Sequence Length: 451

• Applicable Applications for anti-NMT1 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:50-1:200
• Immunogen: Synthetic peptide of human NMT1
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NMT1 Polyclonal Antibody at dilution 1:45)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using NMT1 Polyclonal Antibody at dilution 1:45)

Related Product Information for anti-NMT1 antibody

Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein).

Product Categories/Family for anti-NMT1 antibody

Stem Cells

NCBI and Uniprot Product Information

• NCBI GI #: 34782895
• NCBI GeneID: 4836
• Molecular Weight: 48,141 Da
• NCBI Official Full Name: NMT1 protein, partial
• NCBI Official Synonym Full Names: N-myristoyltransferase 1
• NCBI Official Symbol: NMT1
• NCBI Official Synonym Symbols: NMT
• NCBI Protein Information: glycylpeptide N-tetradecanoyltransferase 1; alternative, short form NMT-S; long form, NMT-L; myristoyl-CoA:protein N-myristoyltransferase 1; type I N-myristoyltransferase
• UniProt Protein Name: Glycylpeptide N-tetradecanoyltransferase 1
• Protein Family: Phosphoethanolamine N-methyltransferase
• UniProt Gene Name: NMT1
• UniProt Synonym Gene Names: NMT; NMT 1; Type I N-myristoyltransferase
• UniProt Entry Name: NMT1_HUMAN

NCBI Description

Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]

Uniprot Description

NMT1: Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins. Belongs to the NMT family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.3.1.97; Transferase; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q21.31

Cellular Component: extrinsic to membrane; cytoplasm; plasma membrane; cell junction; cytosol; actin cytoskeleton

Molecular Function: glycylpeptide N-tetradecanoyltransferase activity

Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; viral reproduction; in utero embryonic development; apoptosis; N-terminal peptidyl-glycine N-myristoylation