Rabbit anti-Human NLRP14 Polyclonal Antibody | anti-NLRP14 antibody
NLRP14 Antibody
Gene Names
NLRP14; NOD5; PAN8; GC-LRR; NALP14; CLR11.2
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
NLRP14; Polyclonal Antibody; NLRP14 Antibody; CLR11.2; GC-LRR; NACHT; leucine rich repeat and PYD containing 14; LRR and PYD containing protein 14; LRR and PYD domains-containing protein 14; NAL14_HUMAN; Nalp-iota; NALP14; NLR family; pyrin domain containing 14; NOD5; Nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain; leucine rich repeat and pyrin domain containing 14; PAN8; anti-NLRP14 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
NLRP14 Antibody detects endogenous levels of NLRP14.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-NLRP14 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human NLRP14.
Conjugation
Unconjugated
Similarity
Upon heterologous expression, a small proportion of the isolated Pyrin domain forms homodimers and higher oligomers. Belongs to the NLRP family.
Tissue Specificity
Testis-specific.
Function
May be involved in inflammation and spermatogenesis.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
124,733 Da
NCBI Official Full Name
NACHT, LRR and PYD domains-containing protein 14
NCBI Official Synonym Full Names
NLR family, pyrin domain containing 14
NCBI Official Symbol
NLRP14
NCBI Official Synonym Symbols
NOD5; PAN8; GC-LRR; NALP14; CLR11.2
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 14; NACHT, LRR and PYD containing protein 14; NACHT, leucine rich repeat and PYD containing 14; nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain, leucine rich repe
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 14
Protein Family
UniProt Gene Name
NLRP14
UniProt Synonym Gene Names
NALP14; NOD5
UniProt Entry Name
NAL14_HUMAN
NCBI Description
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]
Uniprot Description
NLRP14: May be involved in inflammation and spermatogenesis. Belongs to the NLRP family.
Chromosomal Location of Human Ortholog: 11p15.4
Molecular Function: ATP binding
Biological Process: multicellular organismal development; spermatogenesis; cell differentiation
Research Articles on NLRP14
Similar Products
Product Notes
The NLRP14 nlrp14 (Catalog #AAA9630247) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NLRP14 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NLRP14 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the NLRP14 nlrp14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NLRP14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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