Western Blot (WB)
(Mouse Acvr1c Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Acvr1c antibody detected the Acvr1c protein (arrow).)
Rabbit Acvr1c Polyclonal Antibody | anti-Acvr1c antibody
Mouse Acvr1c Antibody (C-term)
Western Blot (WB)
(Mouse Acvr1c Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Acvr1c antibody detected the Acvr1c protein (arrow).)
Western Blot (WB)
(Mouse Acvr1c Antibody (C-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Acvr1c antibody detected the Acvr1c protein (arrow).)
Bertolino, P., et al. Proc. Natl. Acad. Sci. U.S.A. 105(20):7246-7251(2008)
Liguori, G.L., et al. Dev. Biol. 315(2):280-289(2008)
Kurrasch, D.M., et al. J. Neurosci. 27(50):13624-13634(2007)
Kogame, M., et al. J. Med. Invest. 53 (3-4), 238-245 (2006) :
NCBI and Uniprot Product Information
Uniprot Description
ALK7: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.11.30; Protein kinase, TKL; Kinase, protein; Protein kinase, Ser/Thr (receptor); Membrane protein, integral; TKL group; STKR family; Type1 subfamily
Cellular Component: cell surface; membrane; cytoplasm; integral to membrane; plasma membrane; activin receptor complex
Molecular Function: metal ion binding; nucleotide binding; transmembrane receptor protein serine/threonine kinase activity; protein kinase activity; transferase activity; protein serine/threonine kinase activity; activin receptor activity, type I; growth factor binding; transferase activity, transferring phosphorus-containing groups; activin binding; kinase activity; SMAD binding; ATP binding; receptor signaling protein serine/threonine kinase activity
Biological Process: transforming growth factor beta receptor complex assembly; response to dietary excess; trophectodermal cell proliferation; apoptosis; in utero embryonic development; positive regulation of apoptosis; activin receptor signaling pathway; positive regulation of caspase activity; protein amino acid phosphorylation; negative regulation of insulin secretion; response to insulin stimulus; regulation of apoptosis; sequestering of lipid; apoptotic nuclear changes; transmembrane receptor protein serine/threonine kinase signaling pathway; response to glucose stimulus; determination of left/right symmetry; cell differentiation; phosphorylation
Research Articles on Acvr1c
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Product Notes
The Acvr1c acvr1c (Catalog #AAA9215235) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 341-368. The Mouse Acvr1c Antibody (C-term) reacts with Mouse (Predicted Reactivity: Human, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Acvr1c can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Acvr1c acvr1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Acvr1c, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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