Rabbit anti-Human, Mouse NLGN4Y Polyclonal Antibody | anti-NLGN4Y antibody

Rabbit anti-human NLGN4Y polyclonal Antibody

Cat. Num. AAA1492920

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purified
• Synonyms: NLGN4Y; Polyclonal Antibody; Rabbit anti-human NLGN4Y polyclonal Antibody; Neuroligin-4; Y-linked (Neuroligin Y); KIAA0951; anti-NLGN4Y antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 256

• Applicable Applications for anti-NLGN4Y antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Recommended dilution: WB:1:500-2000; IHC:1:20-1:200
• Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Conjugate: Non-conjugated
• Immunogen: Recombinant human Neuroligin-4, Y-linked protein (682-816aa)
• Species: Human
• Research Area: Neuroscience
• Preparation and Storage: Upon receipt, aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(All lanes: NLGN4Y antibody at 6ug/mlLane 1:A549 whole cell lysateLane 2:mouse brain tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 93,73,16,29 kDaObserved band size: 93 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate using MBS1492920 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta using MBS1492920 at dilution 1:100)

Related Product Information for anti-NLGN4Y antibody

Putative neuronal cell surface protein involved in cell-cell-interactions.

NCBI and Uniprot Product Information

• NCBI GI #: 256222832
• NCBI GeneID: 22829
• NCBI Accession #: NP_001157710.1
• NCBI GenBank Nucleotide #: NM_001164238.1
• UniProt Accession #: Q8NFZ3; Q14D08; Q7Z3T5; Q8N5B6; Q9Y2F8; F5H6W0
• NCBI Official Full Name: neuroligin-4, Y-linked isoform 2
• NCBI Official Synonym Full Names: neuroligin 4, Y-linked
• NCBI Official Symbol: NLGN4Y
• NCBI Protein Information: neuroligin-4, Y-linked
• UniProt Protein Name: Neuroligin-4, Y-linked
• Protein Family: Neuroligin
• UniProt Gene Name: NLGN4Y
• UniProt Synonym Gene Names: KIAA0951; Neuroligin Y
• UniProt Entry Name: NLGNY_HUMAN

NCBI Description

This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]

Uniprot Description

NLGN4Y: Putative neuronal cell surface protein involved in cell- cell-interactions. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: Yq11.221

Cellular Component: cell junction; cell surface; extracellular space; integral to plasma membrane; postsynaptic density; postsynaptic membrane; synapse

Molecular Function: cell adhesion molecule binding; neurexin binding; protein binding; receptor activity

Biological Process: learning; neuron adhesion; regulation of synaptic transmission; social behavior; synaptic vesicle endocytosis