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Western Blot (WB) (Western blot analysis of NKX2-6 in mouse spleen tissue lysate with NKX2-6 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)

Rabbit anti-Human, Mouse NKX2-6 Polyclonal Antibody | anti-NKX2-6 antibody

NKX2-6 Antibody

Gene Names
Nkx2-6; Tix; Nkx2.6; tinman; Nkx-2.6; AV044928
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
NKX2-6; Polyclonal Antibody; NKX2-6 Antibody; NK2 homeobox 6; NKX2F; NKX4-2; CSX; anti-NKX2-6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
NKX2-6 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-6 are known to exist; this antibody will detect both isoforms
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
228
Applicable Applications for anti-NKX2-6 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide near the center of human NKX2-6.
Target Name
NKX2-6
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of NKX2-6 in mouse spleen tissue lysate with NKX2-6 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot analysis of NKX2-6 in mouse spleen tissue lysate with NKX2-6 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-NKX2-6 antibody
NKX2-6 (NK2 homeobox 6) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-6 is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are thought to be a cause for some congenital heart abnormalities.
Product Categories/Family for anti-NKX2-6 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
31,597 Da
NCBI Official Full Name
Nkx2-6 protein, partial
NCBI Official Synonym Full Names
NK2 homeobox 6
NCBI Official Symbol
Nkx2-6
NCBI Official Synonym Symbols
Tix; Nkx2.6; tinman; Nkx-2.6; AV044928
NCBI Protein Information
homeobox protein Nkx-2.6
UniProt Protein Name
Homeobox protein Nkx-2.6
Protein Family
UniProt Gene Name
Nkx2-6
UniProt Synonym Gene Names
Nkx-2.6; Nkx2f
UniProt Entry Name
NKX26_MOUSE

Uniprot Description

NKX2-6: In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development. Defects in NKX2-6 may be a cause of conotruncal heart malformations (CTHM). CTHM defines a group of congenital heart defects involving the outflow tracts. Examples include truncus arteriosus communis, double-outlet right ventricle and transposition of great arteries. Truncus arteriosus communis is characterized by a single outflow tract instead of a separate aorta and pulmonary artery. In transposition of the great arteries, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle. In double outlet of the right ventricle, both the pulmonary artery and aorta arise from the right ventricle. Belongs to the NK-2 homeobox family.

Protein type: DNA-binding

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; transcription factor activity

Biological Process: pharyngeal system development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; heart development; multicellular organismal development; positive regulation of cell proliferation; embryonic heart tube development; cell differentiation; negative regulation of apoptosis

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Product Notes

The NKX2-6 nkx2-6 (Catalog #AAA9405207) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NKX2-6 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NKX2-6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the NKX2-6 nkx2-6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NKX2-6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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