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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7044128 at dilution 1:100)

Rabbit anti-Human NINL Polyclonal Antibody | anti-NINL antibody

NINL Antibody

Gene Names
NINL; NLP
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
NINL; Polyclonal Antibody; NINL Antibody; Ninein-like protein; KIAA0980; NLP; anti-NINL antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
1033
Applicable Applications for anti-NINL antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human Ninein-like protein (N-190AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-85793 / sc-85794
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7044128 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7044128 at dilution 1:100)
Related Product Information for anti-NINL antibody
Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
118,447 Da
NCBI Official Full Name
ninein-like protein isoform 2
NCBI Official Synonym Full Names
ninein like
NCBI Official Symbol
NINL
NCBI Official Synonym Symbols
NLP
NCBI Protein Information
ninein-like protein
UniProt Protein Name
Ninein-like protein
Protein Family
UniProt Gene Name
NINL
UniProt Synonym Gene Names
KIAA0980; NLP
UniProt Entry Name
NINL_HUMAN

Uniprot Description

Nlp: a centrosomal protein that may play a role in microtubule organization. Interacts with the gamma-tubulin ring complex and stimulates microtubule nucleation. Phosphorylation by PLK1 disrupts both its centrosome association and its gamma-tubulin interaction. Expressed in KYSE150 esophageal carcinoma, HeLa cervical carcinoma and U2OS osteosarcoma cells. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase (at protein level). Expressed in fetal heart, skeletal muscle, liver, lung and cochlea, and in adult brain, testis, kidney and retina. Ubiquitinated by the APC/C complex leading to its degradation.

Protein type: Cell cycle regulation; Microtubule-binding

Chromosomal Location of Human Ortholog: 20p11.22-p11.1

Cellular Component: cytosol

Molecular Function: protein binding

Biological Process: G2/M transition of mitotic cell cycle

Research Articles on NINL

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Product Notes

The NINL ninl (Catalog #AAA7044128) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NINL Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NINL can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the NINL ninl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NINL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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