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Testing Data

Rabbit anti-Human NGB Polyclonal Antibody | anti-NGB antibody

NGB Antibody

Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
NGB; Polyclonal Antibody; NGB Antibody; anti-NGB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 1% BSA and 0.02% NaN3.
Sequence Length
151
Applicable Applications for anti-NGB antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Peptide ELISA titer: 1:1,000-1:10,000
IHC:1:50-200.
Reconstitution
Reconstitute in 200ul sterile H2O.
Preparation and Storage
The Lyophilized antibody is stable for at least one year when stored at 4 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data
Related Product Information for anti-NGB antibody
Rabbit polyclonal NGB (1) antibody was raised against a 16 amino acid peptide from near the N terminal residues of human NGB protein.
References
(1) Nadra, A.D., Marti, M.A., Pesce, A., et, al. Exploring the molecular basis of heme coordination in human neuroglobin Proteins 71 (2), 695-705 (2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,933 Da
NCBI Official Full Name
neuroglobin
NCBI Official Synonym Full Names
neuroglobin
NCBI Official Symbol
NGB
NCBI Protein Information
neuroglobin
UniProt Protein Name
Neuroglobin
Protein Family
UniProt Gene Name
NGB

NCBI Description

This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008]

Uniprot Description

Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.

Research Articles on NGB

Similar Products

Product Notes

The NGB ngb (Catalog #AAA854467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NGB Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NGB can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Peptide ELISA titer: 1:1,000-1:10,000 IHC:1:50-200. Researchers should empirically determine the suitability of the NGB ngb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NGB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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