Western Blot (WB)
(NFE2L1 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the NFE2L1 antibody detected the NFE2L1 protein (arrow).)
Rabbit anti-Human, Mouse NFE2L1 Polyclonal Antibody | anti-NFE2L1 antibody
NFE2L1, CT (NFE2L1, HBZ17, NRF1, TCF11, Nuclear factor erythroid 2-related factor 1, Locus control region-factor 1, Nuclear factor, erythroid derived 2, like 1, Transcription factor 11, Transcription factor HBZ17, Transcription factor LCR-F1) (Biotin)
Gene Names
NFE2L1; NRF1; TCF11; LCR-F1
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
NFE2L1; Polyclonal Antibody; CT (NFE2L1; HBZ17; NRF1; TCF11; Nuclear factor erythroid 2-related factor 1; Locus control region-factor 1; Nuclear factor; erythroid derived 2; like 1; Transcription factor 11; Transcription factor HBZ17; Transcription factor LCR-F1) (Biotin); Transcription factor LCR-F1; anti-NFE2L1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-NFE2L1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
NFE2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 712-742 amino acids from the C-terminal region of human NFE2L1.
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(NFE2L1 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the NFE2L1 antibody detected the NFE2L1 protein (arrow).)
Western Blot (WB)
(NFE2L1 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the NFE2L1 antibody detected the NFE2L1 protein (arrow).)
Related Product Information for anti-NFE2L1 antibody
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1.
Product Categories/Family for anti-NFE2L1 antibody
References
Steffen, J., et al. Mol. Cell 40(1):147-158(2010). Radhakrishnan, S.K., et al. Mol. Cell 38(1):17-28(2010). Wang, W., et al. J. Biol. Chem. 282(34):24670-24678(2007). Newman, J.R., et al. Science 300(5628):2097-2101(2003). Toki, T., et al. Oncogene 14(16):1901-1910(1997).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
84,704 Da
NCBI Official Full Name
nuclear factor erythroid 2-related factor 1
NCBI Official Synonym Full Names
nuclear factor, erythroid 2-like 1
NCBI Official Symbol
NFE2L1
NCBI Official Synonym Symbols
NRF1; TCF11; LCR-F1
NCBI Protein Information
nuclear factor erythroid 2-related factor 1; TCF-11; NFE2-related factor 1; NF-E2-related factor 1; transcription factor HBZ17; transcription factor LCR-F1; locus control region-factor 1; nuclear factor (erythroid-derived 2)-like 1; nuclear factor, erythr
UniProt Protein Name
Nuclear factor erythroid 2-related factor 1
Protein Family
UniProt Gene Name
NFE2L1
UniProt Synonym Gene Names
HBZ17; NRF1; TCF11; NF-E2-related factor 1; NFE2-related factor 1; TCF-11
UniProt Entry Name
NF2L1_HUMAN
NCBI Description
This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008]
Uniprot Description
NFE2L1: Activates erythroid-specific, globin gene expression. Interacts with KEAP1. Belongs to the bZIP family. CNC subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 17q21.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane; nucleus
Molecular Function: transcription cofactor activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; anatomical structure morphogenesis; erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; inflammatory response; heme biosynthetic process
Research Articles on NFE2L1
Similar Products
Product Notes
The NFE2L1 nfe2l1 (Catalog #AAA6324973) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NFE2L1, CT (NFE2L1, HBZ17, NRF1, TCF11, Nuclear factor erythroid 2-related factor 1, Locus control region-factor 1, Nuclear factor, erythroid derived 2, like 1, Transcription factor 11, Transcription factor HBZ17, Transcription factor LCR-F1) (Biotin) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NFE2L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the NFE2L1 nfe2l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NFE2L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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