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Rabbit anti-Human Neurotensin Polyclonal Antibody | anti-NTS antibody

Neurotensin

Gene Names
NTS; NN; NT; NT/N; NTS1; NMN-125
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by immunoaffinity chromatography
Synonyms
Neurotensin; Polyclonal Antibody; Anti -Neurotensin; anti-NTS antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Neurotensin.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography
Form/Format
Supplied as a liquid in PBS, 0.1% BSA
Applicable Applications for anti-NTS antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1-10ug/ml using ECL.
ELISA: 1:100,000
Immunogen
Synthetic peptide, 13aa corresponding to the N terminal of human Neurotensin. Species sequence homology: mouse, rat, bovine and canine 100%; guinea pig 92%. No significant sequence homology exists with other neuromedins.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-NTS antibody
Neurotensin (NT) is an endogenous tridecapeptide neurotransmitter (pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg- pro-Tyr-Ile-Leu-OH) that was originally isolated from bovine hypothalamus. NT influences distinct central and peripheral physiological functions in mammals. Central administration of NT modulates dopaminergic transmission and triggers hypothermic and naloxone-insensitive analgesic responses, whereas peripheral effects include hypotension, decrease gastric acid release, potentiation of lipid digestion. NT causes contraction of smooth muscle. NT is widely distributed throughout the CNS. It has been localized to catecholamine-containing neurons. NT gene (human chromosome 12q21) produces both NT and neuromedin N
Product Categories/Family for anti-NTS antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,795 Da
NCBI Official Full Name
neurotensin/neuromedin N preproprotein
NCBI Official Synonym Full Names
neurotensin
NCBI Official Symbol
NTS
NCBI Official Synonym Symbols
NN; NT; NT/N; NTS1; NMN-125
NCBI Protein Information
neurotensin/neuromedin N; pro-neurotensin/neuromedin
UniProt Protein Name
Neurotensin/neuromedin N
Protein Family
UniProt Gene Name
NTS
UniProt Synonym Gene Names
NN; NmN; NT
UniProt Entry Name
NEUT_HUMAN

NCBI Description

This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Jul 2008]

Uniprot Description

NTS: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle. Belongs to the neurotensin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q21

Cellular Component: transport vesicle; extracellular region

Molecular Function: neuropeptide hormone activity; protein binding

Biological Process: signal transduction; regulation of blood vessel size

Research Articles on NTS

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Product Notes

The NTS nts (Catalog #AAA622918) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Neurotensin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Neurotensin can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Western Blot: 1-10ug/ml using ECL. ELISA: 1:100,000. Researchers should empirically determine the suitability of the NTS nts for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neurotensin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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