Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Human Neuropilin 2 Polyclonal Antibody | anti-NRP2 antibody
Polyclonal Antibody to Neuropilin 2 (NRP2)
Immunohistochemistry: 5-20 ug/mL;1:22-90
Immunocytochemistry: 5-20 ug/mL;1:22-90
Optimal working dilutions must be determined by end user
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded ovary tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded ovary tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Prostate Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Prostate Tissue))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
NRP2: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Heterodimer with NRP1. Binds PLXNB1. Belongs to the neuropilin family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc.
Chromosomal Location of Human Ortholog: 2q33.3
Cellular Component: extracellular region; integral component of membrane; membrane; plasma membrane
Molecular Function: cytokine binding; growth factor binding; heparin binding; metal ion binding; protein binding; receptor activity; semaphorin receptor activity; vascular endothelial growth factor-activated receptor activity
Biological Process: angiogenesis; axon extension involved in axon guidance; axon guidance; cell adhesion; nerve development; outflow tract septum morphogenesis; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; semaphorin-plexin signaling pathway involved in neuron projection guidance; vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor signaling pathway
Research Articles on NRP2
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Product Notes
The NRP2 nrp2 (Catalog #AAA2027380) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Neuropilin 2 (NRP2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Neuropilin 2 can be used in a range of immunoassay formats including, but not limited to, WB; IHC; ICC; IP. Western blotting: 0.5-2 ug/mL;1:220-900 Immunohistochemistry: 5-20 ug/mL;1:22-90 Immunocytochemistry: 5-20 ug/mL;1:22-90 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the NRP2 nrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neuropilin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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