Western Blot (WB)
(Western blot analysis of NEURL Antibody (Center) in Y79 cell line lysates (35ug/lane). NEURL (arrow) was detected using the purified Pab.)
Rabbit anti-Human NEURL Polyclonal Antibody | anti-NEURL1 antibody
NEURL Antibody (Center)
Western Blot (WB)
(Western blot analysis of NEURL Antibody (Center) in Y79 cell line lysates (35ug/lane). NEURL (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of NEURL Antibody (Center) in Y79 cell line lysates (35ug/lane). NEURL (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human brain tissue reacted with NEURL Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human brain tissue reacted with NEURL Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
NEURL1: May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor; Cell development/differentiation; Motility/polarity/chemotaxis; Ubiquitin ligase; Ligase; Ubiquitin conjugating system; EC 6.3.2.-
Chromosomal Location of Human Ortholog: 10q25.1
Cellular Component: postsynaptic membrane; perinuclear region of cytoplasm; postsynaptic density; dendritic spine; plasma membrane; perikaryon; cell junction
Molecular Function: translation factor activity, non-nucleic acid binding; zinc ion binding; ubiquitin-protein ligase activity; ligase activity
Biological Process: lactation; protein monoubiquitination; positive regulation of filopodium formation; nervous system development; Notch signaling pathway; positive regulation of apoptosis; positive regulation of long-term neuronal synaptic plasticity; regulation of translation; negative regulation of cell proliferation; sperm motility; positive regulation of epidermal growth factor receptor activity; sperm axoneme assembly; negative regulation of Notch signaling pathway
Research Articles on NEURL1
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Product Notes
The NEURL1 neurl1 (Catalog #AAA9210396) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 158-186. The NEURL Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NEURL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the NEURL1 neurl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NEURL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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