Rabbit anti-Human NEDL2 Polyclonal Antibody | anti-NEDL2 antibody
NEDL2 Polyclonal Conjugated Antibody
Gene Names
HECW2; NEDL2
Reactivity
Human
Applications
Most Applications
Synonyms
NEDL2; Polyclonal Antibody; NEDL2 Polyclonal Conjugated Antibody; HECW2; KIAA1301; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2; anti-NEDL2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
NEDL2 polyclonal antibody detects endogenous levels of NEDL2 protein.
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-NEDL2 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Synthesized peptide derived from the Internal region of human NEDL2.
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
175,769 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase HECW2
NCBI Official Synonym Full Names
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
NCBI Official Symbol
HECW2
NCBI Official Synonym Symbols
NEDL2
NCBI Protein Information
E3 ubiquitin-protein ligase HECW2; NEDD4-related E3 ubiquitin ligase NEDL2; NEDD4-like E3 ubiquitin-protein ligase 2; HECT, C2 and WW domain-containing protein 2
UniProt Protein Name
E3 ubiquitin-protein ligase HECW2
UniProt Gene Name
HECW2
UniProt Synonym Gene Names
KIAA1301; NEDL2
UniProt Entry Name
HECW2_HUMAN
Uniprot Description
HECW2: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system; Ligase; EC 6.3.2.19; EC 6.3.2.-; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 2q32.3
Cellular Component: cytoplasm; nucleus
Molecular Function: ubiquitin-protein ligase activity; ligase activity
Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process
Research Articles on NEDL2
Similar Products
Product Notes
The NEDL2 hecw2 (Catalog #AAA9449959) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NEDL2 Polyclonal Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NEDL2 can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the NEDL2 hecw2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NEDL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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