Rabbit NDUFAF1 Polyclonal Antibody | anti-NDUFAF1 antibody

Anti-NDUFAF1 Antibody

Cat. Num. AAA8307404

• Gene Names: NDUFAF1; CGI65; CIA30; CGI-65
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: Purified by Immunogen Affinity Chromatography
• Synonyms: NDUFAF1; Polyclonal Antibody; Anti-NDUFAF1 Antibody; CIA30; Complex I intermediate-associated protein 30 mitochondrial; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1; anti-NDUFAF1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Recognizes endogenous levels of NDUFAF1 protein.
• Purity/Purification: Purified by Immunogen Affinity Chromatography
• Form/Format: Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.

• Applicable Applications for anti-NDUFAF1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant fusion protein of human NDUFAF1. The exact sequence is proprietary.
• Preparation and Storage: Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of NDUFAF1 expression in HeLa (A), mouse heart (B), rat liver (C) whole cell lysates.)

Related Product Information for anti-NDUFAF1 antibody

Rabbit polyclonal antibody to NDUFAF1

NCBI and Uniprot Product Information

• NCBI GI #: 49574510
• NCBI GeneID: 51103
• NCBI Accession #: NP_057097.2
• NCBI GenBank Nucleotide #: NM_016013.3
• UniProt Accession #: Q9Y375; Q9CWX2
• Molecular Weight: 37,764 Da
• NCBI Official Full Name: complex I intermediate-associated protein 30, mitochondrial
• NCBI Official Synonym Full Names: NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
• NCBI Official Symbol: NDUFAF1
• NCBI Official Synonym Symbols: CGI65; CIA30; CGI-65
• NCBI Protein Information: complex I intermediate-associated protein 30, mitochondrial; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1; NADH-ubiquinone oxidoreductase 1 alpha subcomplex, assembly factor 1
• UniProt Protein Name: Complex I intermediate-associated protein 30, mitochondrial
• UniProt Gene Name: NDUFAF1
• UniProt Synonym Gene Names: CIA30
• UniProt Entry Name: CIA30_HUMAN

NCBI Description

This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011]

Uniprot Description

NDUFAF1: Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Belongs to the CIA30 family.

Chromosomal Location of Human Ortholog: 15q11.2-q21.3

Cellular Component: cytoplasm; mitochondrial respiratory chain complex I

Molecular Function: protein binding; unfolded protein binding

Biological Process: mitochondrial electron transport, NADH to ubiquinone; protein complex assembly

Disease: Mitochondrial Complex I Deficiency