Rabbit anti-Human, Rat NDUC2 Polyclonal Antibody | anti-NDUC2 antibody

NDUC2 polyclonal antibody

Cat. Num. AAA3000867

• Gene Names: NDUFC2; HLC-1; B14.5b; NADHDH2; CI-B14.5b
• Reactivity: Human, Rat
• Applications: Immunohistochemistry, Immunofluorescence, ELISA
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: NDUC2; Polyclonal Antibody; NDUC2 polyclonal antibody; NDUFC2; HLC1; NADH dehydrogenase [ubiquinone] 1 subunit C2; Complex I-B14.5b; CI-B14.5b; Human lung cancer oncogene 1 protein; HLC-1; NADH-ubiquinone oxidoreductase subunit B14.5b; anti-NDUC2 antibody

• Host: Rabbit
• Reactivity: Human, Rat
• Clonality: Polyclonal
• Specificity: NDUFC2 Polyclonal Antibody detects endogenous levels of NDUFC2 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-NDUC2 antibody: Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)(paraffin section), ELISA (EIA)
• Application Notes: IHC: 1/100-1/300; ELISA: 1/10,000
• Immunogen: The antiserum was produced against synthesized peptide derived from human NDUC2. AA range: 51-100
• Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
• Similarity: Belongs to the complex I NDUFC2 subunit family.
• Subunit: Complex I is composed of 45 different subunits.
• Preparation and Storage: Store at 4 degee C for short term. Aliquot and store at -20 degee C long term. Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NDUC2 Antibody. The picture on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 323276603
• NCBI GeneID: 4718
• NCBI Accession #: NP_001190983.1
• NCBI GenBank Nucleotide #: NM_001204054.1
• UniProt Accession #: O95298; Q549M5; Q6FIH8; Q9UBJ9
• Molecular Weight: 14,188 Da
• NCBI Official Full Name: NADH dehydrogenase
• NCBI Official Synonym Full Names: NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
• NCBI Official Symbol: NDUFC2
• NCBI Official Synonym Symbols: HLC-1; B14.5b; NADHDH2; CI-B14.5b
• NCBI Protein Information: NADH dehydrogenase [ubiquinone] 1 subunit C2; NADH dehydrogenase [ubiquinone] 1 subunit C2; complex I-B14.5b; complex I subunit B14.5b; human lung cancer oncogene 1 protein; NADH-ubiquinone oxidoreductase subunit B14.5b
• UniProt Protein Name: NADH dehydrogenase [ubiquinone] 1 subunit C2
• UniProt Gene Name: NDUFC2
• UniProt Synonym Gene Names: CI-B14.5b; HLC-1
• UniProt Entry Name: NDUC2_HUMAN

Uniprot Description

NDUFC2: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFC2 subunit family.

Protein type: Membrane protein, integral; Mitochondrial; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 11q14.1

Cellular Component: mitochondrial inner membrane; cytoplasm; integral to membrane; mitochondrial respiratory chain complex I

Molecular Function: NADH dehydrogenase (ubiquinone) activity

Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone