Western Blot (WB)
(Western Blot (WB) analysis of NDRG2 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate Lane2:Raw264. 7 whole cell lysateLane3:PC12 whole cell lysateLane4:HELA whole cell lysate)
Rabbit NDRG2 Polyclonal Antibody | anti-NDRG2 antibody
NDRG2 Polyclonal Antibody
Gene Names
NDRG2; SYLD
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
NDRG2; Polyclonal Antibody; NDRG2 Polyclonal Antibody; Protein NDRG2; N-myc downstream-regulated gene 2 protein; Protein Syld709613; KIAA1248; SYLD; anti-NDRG2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
NDRG2 polyclonal antibody detects endogenous levels of NDRG2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
367
Applicable Applications for anti-NDRG2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human NDRG2.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of NDRG2 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate Lane2:Raw264. 7 whole cell lysateLane3:PC12 whole cell lysateLane4:HELA whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of NDRG2 polyclonal antibody at 1:500 dilutionLane1:HEK293T whole cell lysate Lane2:Raw264. 7 whole cell lysateLane3:PC12 whole cell lysateLane4:HELA whole cell lysate)
Related Product Information for anti-NDRG2 antibody
The N-myc downstream regulated gene (NDRG) family is comprised of four members, namely NDRG1, NDRG2, NDRG3 and NDRG4, all of which share 57-65% homology. NDRG2 (NDRG family member 2), also known as SYLD, is a 371 amino acid protein that localizes to both the cytoplasm and the perinuclear region in neurons. Expressed at high levels in heart, brain, dendritic cells, salivary gland and skeletal muscle and at lower levels in liver and kidney, NDRG2 is thought to be involved in dendritic and neuronal cell differentiation and outgrowth. Additionally, NDRG2 expression is downregulated in a variety of carcinomas, including liver cancer, pancreatic cancer and meningioma, suggesting a possible role for NDRG2 in tumor suppression. NDRG2 is found in brain lesions of Alzheimer Disease (AD)-affected patients and is thought to be associated with the progression of AD. Five isoforms of NDRG2 exist due to alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 41kDa
NCBI Official Full Name
protein NDRG2 isoform c
NCBI Official Synonym Full Names
NDRG family member 2
NCBI Official Symbol
NDRG2
NCBI Official Synonym Symbols
SYLD
NCBI Protein Information
protein NDRG2
UniProt Protein Name
Protein NDRG2
Protein Family
UniProt Gene Name
NDRG2
UniProt Synonym Gene Names
KIAA1248; SYLD
UniProt Entry Name
NDRG2_HUMAN
NCBI Description
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Research Articles on NDRG2
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Product Notes
The NDRG2 ndrg2 (Catalog #AAA3007284) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NDRG2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NDRG2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the NDRG2 ndrg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NDRG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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