Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Mouse liver tissue and A172 cell, human prostate tissue Amount of lysate: 40ug per lane Primary antibody: 1/1500 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Rabbit anti-Human, Mouse NDNL2 Polyclonal Antibody | anti-NDNL2 antibody
NDNL2 Antibody
Immunohistochemistry: 1:25-1:100
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Mouse liver tissue and A172 cell, human prostate tissue Amount of lysate: 40ug per lane Primary antibody: 1/1500 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Mouse liver tissue and A172 cell, human prostate tissue Amount of lysate: 40ug per lane Primary antibody: 1/1500 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/40.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/40.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. [provided by RefSeq, May 2011]
Uniprot Description
MAGE-G1: Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs). In vitro enhances ubiquitin ligase activity of NSMCE1. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May be a growth suppressor that facilitates the entry of the cell into cell cycle arrest.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 15q13.1
Cellular Component: chromosome, telomeric region; cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: positive regulation of protein ubiquitination; regulation of growth; DNA repair; DNA recombination
Research Articles on NDNL2
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Product Notes
The NDNL2 ndnl2 (Catalog #AAA9413369) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NDNL2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NDNL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:2000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the NDNL2 ndnl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NDNL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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