Rabbit anti-Human NCKX3 Polyclonal Antibody
NCKX3 (Sodium/Potassium/Calcium Exchanger 3, a(+)/K(+)/Ca(2+)-exchange Protein 3, Solute Carrier Family 24 Member 3, SLC24A3)
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
NCKX3; Polyclonal Antibody; NCKX3 (Sodium/Potassium/Calcium Exchanger 3; a(+)/K(+)/Ca(2+)-exchange Protein 3; Solute Carrier Family 24 Member 3; SLC24A3); Anti -NCKX3 (Sodium/Potassium/Calcium Exchanger 3; anti-NCKX3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human NCKX3. Does not recognize human NCKX1-2 or other NCXs.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 0.1% BSA. Reconstitute with 100ul sterile PBS.
Applicable Applications for anti-NCKX3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 0.5-1ug/ml. Control peptide can be used to coat ELISA plate at 1ug/ml.
Western Blot: 1-10ug/ml (ECL)
Dilution: ELISA: 0.5-1ug/ml. Control peptide can be used to coat ELISA plate at 1ug/ml.
Western Blot: 1-10ug/ml (ECL)
Immunogen
Synthetic peptide corresponding to 16aa near the C-terminal, extracellular domain of human NCKX3 conjugated to KLH. Species Sequence Homology: mouse and rat, 100%
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-NCKX3 antibody
Ca2+ plays a critical role in intracellular signaling. Intracellular Ca2+ levels are tightly controlled by continuos removal of Ca2+ via ATP-driven Ca2+ pump in the endoplasmic reticulum and plasma membrane, and the Na+/Ca2+ exchangers (NCX), in the plasma membrane. NCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In most cells, 3 Na+ are exchanged for 1 Ca2+. Several genes code for the 3 NCX (NCX1, NCX2, and NCX3), and three in the NCKX family (NCKX1, NCKX2, NCKX3). NCX share significant sequence homology (~70%), display 11 TM domains, a large central, intracellular hydrophilic regulatory loop between TM5 and 6, extracellular N-terminus and cytoplasmic C-terminus. The N-terminal signal peptide is cleaved off from the mature exchanger protein.
Product Categories/Family for anti-NCKX3 antibody
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Product Notes
The NCKX3 (Catalog #AAA627485) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NCKX3 (Sodium/Potassium/Calcium Exchanger 3, a(+)/K(+)/Ca(2+)-exchange Protein 3, Solute Carrier Family 24 Member 3, SLC24A3) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NCKX3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 0.5-1ug/ml. Control peptide can be used to coat ELISA plate at 1ug/ml. Western Blot: 1-10ug/ml (ECL). Researchers should empirically determine the suitability of the NCKX3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NCKX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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