<
Immunohistochemistry (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit NCF2/NOXA2/p67phox Polyclonal Antibody | anti-NCF2 antibody
Anti-NCF2/NOXA2/p67phox Antibody
Gene Names
NCF2; NCF-2; NOXA2; P67PHOX; P67-PHOX
Reactivity
HumanPredicted: Mouse, Rat
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Affinity Purified
Synonyms
NCF2/NOXA2/p67phox; Polyclonal Antibody; Anti-NCF2/NOXA2/p67phox Antibody; Rabbit Polyclonal (IgG) to Human NCF2/NOXA2/p67phox; NCF2; NADPH oxidase activator 2; Neutrophil cytosol factor 2; Neutrophil cytosolic factor 2; NOXA2; p67PHOX; NCF-2; p67-PHOX; anti-NCF2 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Human NCF2/NOXA2/p67phox
Purity/Purification
Affinity Purified
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Sequence Length
526
Applicable Applications for anti-NCF2 antibody
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ICC: 1:20-1:100
IF: 1:50-1:200
IHC: 1:50-1:200
IHC-P: 1:100
IP: 1:20-1:100
WB: 1:500-1:2000
IF: 1:50-1:200
IHC: 1:50-1:200
IHC-P: 1:100
IP: 1:20-1:100
WB: 1:500-1:2000
Immunogen
Recombinant protein of human NCF2
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (WB)
(Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (WB)
(Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cell using NCF2 antibody. Blue: DAPI for nuclear staining.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cell using NCF2 antibody. Blue: DAPI for nuclear staining.)
Western Blot (WB)
(Western blot analysis of THP1 cell and mouse spleen cell lysate using NCF2 antibody.)
Western Blot (WB)
(Western blot analysis of THP1 cell and mouse spleen cell lysate using NCF2 antibody.)
Western Blot (WB)
(Western blot analysis of THP1 cell and mouse spleen cell lysate.)
Western Blot (WB)
(Western blot analysis of THP1 cell and mouse spleen cell lysate.)
Related Product Information for anti-NCF2 antibody
NOXA2/p67phox is neutrophil cytosolic factor 2, the 67-kilodaltoncytosolic subunit of the multi-protein NADPH oxidase complex found inneutrophils. This oxidase produces a burst of superoxide which isdelivered to the lumen of the neutrophil phagosome. Mutations in thisgene, as well as in other NADPH oxidase subunits, can result in chronicgranulomatous disease, a disease that causes recurrent infections bycatalase-positive organisms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,337 Da
NCBI Official Full Name
neutrophil cytosol factor 2 isoform 1
NCBI Official Synonym Full Names
neutrophil cytosolic factor 2
NCBI Official Symbol
NCF2
NCBI Official Synonym Symbols
NCF-2; NOXA2; P67PHOX; P67-PHOX
NCBI Protein Information
neutrophil cytosol factor 2
UniProt Protein Name
Neutrophil cytosol factor 2
Protein Family
UniProt Gene Name
NCF2
UniProt Synonym Gene Names
NOXA2; P67PHOX; NCF-2
NCBI Description
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
Uniprot Description
NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Research Articles on NCF2
Similar Products
Product Notes
The NCF2 ncf2 (Catalog #AAA2401916) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NCF2/NOXA2/p67phox Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NCF2/NOXA2/p67phox can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (IHC) Paraffin, Immunoprecipitation (IP), Western Blot (WB). ICC: 1:20-1:100 IF: 1:50-1:200 IHC: 1:50-1:200 IHC-P: 1:100 IP: 1:20-1:100 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the NCF2 ncf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NCF2/NOXA2/p67phox, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
