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Immunohistochemistry (IHC) (Anti-NPTX2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit NARP / NPTX2 Polyclonal Antibody | anti-NARP antibody

Rabbit Polyclonal to Human NARP / NPTX2

Gene Names
NPTX2; NP2; NARP; NP-II
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
NARP / NPTX2; Polyclonal Antibody; Rabbit Polyclonal to Human NARP / NPTX2; Anti-NARP / NPTX2 Antibody (Internal) IHC-plus; NPTX2; Apexin; Neuronal pentraxin-2; NARP; Neuronal pentraxin II; NP-II; NP2; Human NARP; anti-NARP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
431
Applicable Applications for anti-NARP antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
16 amino acid peptide near the center of the human NPTX2.
Immunogen
NARP / NPTX2 antibody was raised against 16 amino acid peptide near the center of the human NPTX2.
Antigen Modification
Internal
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-NPTX2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-NPTX2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of NPTX2 in Human Brain cells with NPTX2 antibody at 20 ug/ml.)

Immunofluorescence (IF) (Immunofluorescence of NPTX2 in Human Brain cells with NPTX2 antibody at 20 ug/ml.)

Western Blot (WB)

(Western blot of NPTX2 in mouse brain tissue lysate with NPTX2 antibody at (A) 0.5 and (B) 1 ug/ml.)

Western Blot (WB) (Western blot of NPTX2 in mouse brain tissue lysate with NPTX2 antibody at (A) 0.5 and (B) 1 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,042 Da
NCBI Official Full Name
neuronal pentraxin-2
NCBI Official Synonym Full Names
neuronal pentraxin II
NCBI Official Symbol
NPTX2
NCBI Official Synonym Symbols
NP2; NARP; NP-II
NCBI Protein Information
neuronal pentraxin-2; apexin; neuronal activity-regulated pentaxin
UniProt Protein Name
Neuronal pentraxin-2
UniProt Gene Name
NPTX2
UniProt Synonym Gene Names
NP2; NP-II
UniProt Entry Name
NPTX2_HUMAN

NCBI Description

This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]

Uniprot Description

NPTX2: Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 7q21.3-q22.1

Cellular Component: extracellular region

Molecular Function: metal ion binding; carbohydrate binding

Biological Process: synaptic transmission

Research Articles on NARP

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Product Notes

The NARP nptx2 (Catalog #AAA242655) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human NARP / NPTX2 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NARP / NPTX2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the NARP nptx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NARP / NPTX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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