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Typical Testing Data/Standard Curve (for reference only)

Human neuronal pentraxin II ELISA Kit | NPTX2 elisa kit

Human Neuronal pentraxin-2, NPTX2 ELISA Kit

Gene Names
NPTX2; NP2; NARP; NP-II
Reactivity
Human
Synonyms
neuronal pentraxin II; Human Neuronal pentraxin-2; NPTX2 ELISA Kit; Human Neuronal pentraxin-2 (NPTX2) ELISA kit; NARP; NP-II; NP2; apexin; neuronal activity-regulated pentaxin; NPTX2 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of human NPTX2. No significant cross-reactivity or interference between human NPTX2 and analogues was observed.
Sequence Length
431
Samples
Serum, plasma, tissue homogenates
Assay Type
Quantitative Sandwich
Detection Range
0.156 ng/ml-10 ng/ml
Sensitivity
< 0.039 ng/ml
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for NPTX2 elisa kit
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for NPTX2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any NPTX2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for NPTX2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of NPTX2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,042 Da
NCBI Official Full Name
neuronal pentraxin-2
NCBI Official Synonym Full Names
neuronal pentraxin II
NCBI Official Symbol
NPTX2
NCBI Official Synonym Symbols
NP2; NARP; NP-II
NCBI Protein Information
neuronal pentraxin-2; apexin; neuronal activity-regulated pentaxin
UniProt Protein Name
Neuronal pentraxin-2
Protein Family
UniProt Gene Name
NPTX2
UniProt Synonym Gene Names
NP2; NP-II
UniProt Entry Name
NPTX2_HUMAN

NCBI Description

This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]

Uniprot Description

NPTX2: Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q21.3-q22.1

Cellular Component: extracellular region

Molecular Function: metal ion binding; carbohydrate binding

Biological Process: synaptic transmission

Research Articles on NPTX2

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Product Notes

The Human NPTX2 nptx2 (Catalog #AAA924168) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA924168 ELISA Kit recognizes Human NPTX2. It is sometimes possible for the material contained within the vial of "neuronal pentraxin II, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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