Western Blot (WB)
(The anti-MTMR4 Pab is used in Western blot to detect MTMR4 in mouse heart cell lysate.)
Rabbit anti-Human, Mouse Myotubularin Related Protein 4 Polyclonal Antibody | anti-MTMR4 antibody
Myotubularin Related Protein 4, CT (MTMR4, FYVE Domain-containing Dual Specificity Protein Phosphatase 2, FYVE-DSP2, KIAA0647, Zinc Finger FYVE Domain-containing Protein 11, ZFYVE11)
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:10-1:50
Western Blot (WB)
(The anti-MTMR4 Pab is used in Western blot to detect MTMR4 in mouse heart cell lysate.)
Western Blot (WB)
(The anti-MTMR4 Pab is used in Western blot to detect MTMR4 in mouse heart cell lysate.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with MTMR4 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with MTMR4 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
MTMR4: Dephosphorylates proteins phosphorylated on Ser, Thr, and Tyr residues and low molecular weight phosphatase substrate para-nitrophenylphosphate. Phosphorylates phosphatidylinositol 3,4,5-trisphosphate (PIP3). Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Protein type: Phosphatase, lipid; Motility/polarity/chemotaxis; EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor); Protein phosphatase, dual-specificity
Chromosomal Location of Human Ortholog: 17q22
Cellular Component: extracellular space; early endosome membrane; cytosol
Molecular Function: protein binding; metal ion binding; protein tyrosine phosphatase activity; protein serine/threonine phosphatase activity
Biological Process: phospholipid metabolic process; transforming growth factor beta receptor signaling pathway; phosphatidylinositol biosynthetic process; response to denervation involved in regulation of muscle adaptation; negative regulation of transforming growth factor beta receptor signaling pathway; protein amino acid dephosphorylation
Research Articles on MTMR4
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Product Notes
The MTMR4 (Catalog #AAA626838) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Myotubularin Related Protein 4, CT (MTMR4, FYVE Domain-containing Dual Specificity Protein Phosphatase 2, FYVE-DSP2, KIAA0647, Zinc Finger FYVE Domain-containing Protein 11, ZFYVE11) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Myotubularin Related Protein 4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the MTMR4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Myotubularin Related Protein 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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