Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (Western Blot: Sample: Mouse Brain Tissue.)

Rabbit anti-Mouse Myosin IA (MYO1A) Polyclonal Antibody | anti-MYO1A antibody

Polyclonal Antibody to Myosin IA (MYO1A)

Gene Names
Myo1a; Myhl; BBM-I
Reactivity
Mouse
Applications
Immunocytochemistry, Immunohistochemistry, ELISA, Western Blot
Purity
Affinity Chromatography
Synonyms
Myosin IA (MYO1A); Polyclonal Antibody; Polyclonal Antibody to Myosin IA (MYO1A); anti-MYO1A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against MYO1A. It has been selected for its ability to recognize MYO1A in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSGSEF- MAQKFLLN LKKNLPSTKV LDNTWPAAPY RCFNTANQEL QRLFYQWKCK KFRDQLSPKQ VQTLREKLCA SELFKGKKAS YPQSVPIPFR GDYIGLQGNP KLQRLKGREE GPVLVADTVK KVNRGNGKTS ARILLLTKGH VILTDAKKSQ AQIVIGLEDV AGVSVSSLQD GLFSLHLSEM SSAVSKGDIL LVSDHVVELL TKMYQAVLDA TQRQLSVTVT EKFSVRFKEG SVAVKVIQGP EGGGNRKLIC KKKGSNAMEV TVR
Sequence Length
1073
Applicable Applications for anti-MYO1A antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunogen
Recombinant MYO1A (Met783~Arg1043) expressed in E.coli.
Cross Reactivity
Mouse
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2041594
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Mouse Brain Tissue.)

Western Blot (WB) (Western Blot: Sample: Mouse Brain Tissue.)

Western Blot (WB)

(Western Blot: Sample: Recombinant MYO1A, Mouse.)

Western Blot (WB) (Western Blot: Sample: Recombinant MYO1A, Mouse.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Mouse Lung Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Mouse Lung Tissue.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Mouse Kidney Tissue)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Mouse Kidney Tissue)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Mouse Testis Tissue.)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Mouse Testis Tissue.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
118,695 Da
NCBI Official Full Name
unconventional myosin-Ia
NCBI Official Synonym Full Names
myosin IA
NCBI Official Symbol
Myo1a
NCBI Official Synonym Symbols
Myhl; BBM-I
NCBI Protein Information
unconventional myosin-Ia
UniProt Protein Name
Unconventional myosin-Ia
Protein Family
UniProt Gene Name
Myo1a
UniProt Synonym Gene Names
Bbmi; Myhl; BBM-I; BBMI; MIHC

Uniprot Description

MYO1A: Involved in directing the movement of organelles along actin filaments (Potential). Defects in MYO1A are the cause of deafness autosomal dominant type 48 (DFNA48). DFNA48 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

Protein type: Actin-binding; Motility/polarity/chemotaxis; Motor

Chromosomal Location of Human Ortholog: 10 D3|10 74.62 cM

Cellular Component: actin cytoskeleton; apical plasma membrane; basal plasma membrane; basolateral plasma membrane; brush border; cell leading edge; cell soma; cortical actin cytoskeleton; cytoplasm; filamentous actin; growth cone; lateral plasma membrane; membrane raft; microvillus; myosin complex; neuron projection

Molecular Function: actin binding; actin filament binding; ATP binding; calmodulin binding; motor activity; nucleotide binding

Biological Process: cell projection organization; microvillus assembly; regulation of protein localization; sensory perception of sound; vesicle localization

Research Articles on MYO1A

Similar Products

Product Notes

The MYO1A myo1a (Catalog #AAA2006137) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Myosin IA (MYO1A) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Myosin IA (MYO1A) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the MYO1A myo1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- MAQKFLLN LKKNLPSTKV LDNTWPAAPY RCFNTANQEL QRLFYQWKCK KFRDQLSPKQ VQTLREKLCA SELFKGKKAS YPQSVPIPFR GDYIGLQGNP KLQRLKGREE GPVLVADTVK KVNRGNGKTS ARILLLTKGH VILTDAKKSQ AQIVIGLEDV AGVSVSSLQD GLFSLHLSEM SSAVSKGDIL LVSDHVVELL TKMYQAVLDA TQRQLSVTVT EKFSVRFKEG SVAVKVIQGP EGGGNRKLIC KKKGSNAMEV TVR. It is sometimes possible for the material contained within the vial of "Myosin IA (MYO1A), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.