Rabbit MYLK3 Polyclonal Antibody | anti-MYLK3 antibody
MYLK3 Antibody FITC
Gene Names
MYLK3; MLCK; MLCK2; caMLCK
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Immobilized antigen affinity chromatography
Synonyms
MYLK3; Polyclonal Antibody; MYLK3 Antibody FITC; FITC-Conjugated Myosin light chain kinase 3 Antibody; caMLCK antibody; cardiac MLCK antibody; Cardiac MyBP C associated Ca/CaM kinase antibody; MLC kinase antibody; MLCK antibody; MLCK2 antibody; Mylk3 antibody; Myosin light chain kinase 3 antibody; Putative myosin light chain kinase 3 antibody; anti-MYLK3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immobilized antigen affinity chromatography
Concentration
0.5-1.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
819
Applicable Applications for anti-MYLK3 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:50,000
IP: 1:200
WB: 1:2,500-1:5,000
IP: 1:200
WB: 1:2,500-1:5,000
Immunogen
Synthetic peptide taken within amino acid region 10-60 on human Myosin light chain kinase 3 protein.
Conjugation
FITC
Molecular Function
ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; myosin light chain kinase activity
Subcellular Location
Cytoplasm
Preparation and Storage
Store at -20 degree C for long term storage.
Related Product Information for anti-MYLK3 antibody
Overview: Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility.
Structure: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Expression: Restricted to heart
Structure: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Expression: Restricted to heart
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
52,723 Da
NCBI Official Full Name
Myosin light chain kinase 3
NCBI Official Synonym Full Names
myosin light chain kinase 3
NCBI Official Symbol
MYLK3
NCBI Official Synonym Symbols
MLCK; MLCK2; caMLCK
NCBI Protein Information
myosin light chain kinase 3
UniProt Protein Name
Myosin light chain kinase 3
Protein Family
UniProt Gene Name
MYLK3
UniProt Synonym Gene Names
MLCK; Cardiac-MLCK
NCBI Description
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008]
Uniprot Description
Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility ().
Research Articles on MYLK3
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Product Notes
The MYLK3 mylk3 (Catalog #AAA5400548) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MYLK3 Antibody FITC reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MYLK3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:50,000 IP: 1:200 WB: 1:2,500-1:5,000. Researchers should empirically determine the suitability of the MYLK3 mylk3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYLK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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