Rabbit anti-Human, Mouse MYF5 Polyclonal Antibody | anti-MYF5 antibody

MYF5 Rabbit pAb

Cat. Num. AAA4758306

• Gene Names: MYF5; bHLHc2
• Reactivity: Human, Mouse
• Applications: ELISA, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: MYF5; Polyclonal Antibody; MYF5 Rabbit pAb; myogenic factor 5; anti-MYF5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-MYF5 antibody: ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: ELISA: 1:1000-1:2000; IHC: 1:25-1:100
• Immunogen: Synthetic peptide of human MYF5
• Conjugation: Unconjugated
• Molecular Function: Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:29887215). Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.
• Modification: Unmodified
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 860620(MYF5 Antibody) at dilution 1/15.(Original magnification: ×200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 860620(MYF5 Antibody) at dilution 1/15. (Original magnification: ×200))

Related Product Information for anti-MYF5 antibody

Basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MRF family members include Myf5, MyoD (Myf3), myogenin, and MRF4 (Myf6).

Product Categories/Family for anti-MYF5 antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 156104906
• NCBI GeneID: 4617
• NCBI Accession #: NP_005584.2
• NCBI GenBank Nucleotide #: NM_005593.2
• UniProt Accession #: P13349; Q6ISR9
• Molecular Weight: 28,296 Da
• NCBI Official Full Name: myogenic factor 5
• NCBI Official Synonym Full Names: myogenic factor 5
• NCBI Official Symbol: MYF5
• NCBI Official Synonym Symbols: bHLHc2
• NCBI Protein Information: myogenic factor 5; myf-5; class C basic helix-loop-helix protein 2
• UniProt Protein Name: Myogenic factor 5
• Protein Family: Myogenic factor
• UniProt Gene Name: MYF5
• UniProt Synonym Gene Names: BHLHC2; Myf-5; bHLHc2
• UniProt Entry Name: MYF5_HUMAN

Uniprot Description

Myf-5: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 12q21

Cellular Component: nucleoplasm

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein heterodimerization activity

Biological Process: transcription from RNA polymerase II promoter; ossification; extracellular matrix organization and biogenesis; muscle development; skeletal muscle development; somitogenesis; camera-type eye development; regulation of cell-matrix adhesion; muscle cell fate commitment; positive regulation of myoblast differentiation; embryonic skeletal morphogenesis; regulation of transcription from RNA polymerase II promoter; muscle cell differentiation; positive regulation of skeletal muscle fiber development; positive regulation of muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; cartilage condensation