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Western Blot (WB) (Western blot analysis of MVD expression in A549 (A), LO2 (B) whole cell lysates.)

Rabbit anti-Human, Mouse MVD Polyclonal Antibody | anti-MVD antibody

Anti-MVD Antibody

Gene Names
MVD; MPD; MDDase; FP17780
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
MVD; Polyclonal Antibody; Anti-MVD Antibody; MPD; Diphosphomevalonate decarboxylase; Mevalonate (diphospho)decarboxylase; MDDase; Mevalonate pyrophosphate decarboxylase; anti-MVD antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of MVD protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Applicable Applications for anti-MVD antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human MVD. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of MVD expression in A549 (A), LO2 (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of MVD expression in A549 (A), LO2 (B) whole cell lysates.)
Related Product Information for anti-MVD antibody
Rabbit polyclonal antibody to MVD

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,405 Da
NCBI Official Full Name
diphosphomevalonate decarboxylase
NCBI Official Synonym Full Names
mevalonate (diphospho) decarboxylase
NCBI Official Symbol
MVD
NCBI Official Synonym Symbols
MPD; MDDase; FP17780
NCBI Protein Information
diphosphomevalonate decarboxylase; mevalonate pyrophosphate decarboxylase
UniProt Protein Name
Diphosphomevalonate decarboxylase
UniProt Gene Name
MVD
UniProt Synonym Gene Names
MPD; MDDase
UniProt Entry Name
MVD1_HUMAN

NCBI Description

The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008]

Uniprot Description

MVD: Performs the first committed step in the biosynthesis of isoprenes. Belongs to the diphosphomevalonate decarboxylase family.

Protein type: Lyase; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; EC 4.1.1.33

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: peroxisome; cytosol

Molecular Function: diphosphomevalonate decarboxylase activity; protein homodimerization activity; Hsp70 protein binding; ATP binding

Biological Process: cellular protein metabolic process; isoprenoid biosynthetic process; isopentenyl diphosphate biosynthetic process, mevalonate pathway; dolichol-linked oligosaccharide biosynthetic process; positive regulation of cell proliferation; dolichyl diphosphate biosynthetic process; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; cholesterol biosynthetic process

Research Articles on MVD

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Product Notes

The MVD mvd (Catalog #AAA8307352) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MVD Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MVD can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MVD mvd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MVD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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