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Rabbit anti-Mouse Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) Polyclonal Antibody | anti-MUSK antibody

FITC-Linked Polyclonal Antibody to Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK)

Gene Names
Musk; Nsk1
Reactivity
Mouse
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Synonyms
Muscle; Skeletal; Receptor Tyrosine Kinase (MUSK); Polyclonal Antibody; FITC-Linked Polyclonal Antibody to Muscle; Muscle-specific tyrosine-protein kinase receptor; Muscle-specific kinase receptor; anti-MUSK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Concentration
500ug/ml (varies by lot)
Applicable Applications for anti-MUSK antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA)
Immunogen
MUSK (Cys517~Arg777)
Conjugation
FITC
Cross Reactivity
Human, Mouse
Unconjugated Antibody
The unconjugated antibody version of this item is also available as catalog #MBS2002046

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
96,822 Da
NCBI Official Full Name
muscle, skeletal receptor tyrosine protein kinase
NCBI Official Synonym Full Names
muscle associated receptor tyrosine kinase
NCBI Official Symbol
Musk
NCBI Official Synonym Symbols
Nsk1
NCBI Protein Information
muscle, skeletal receptor tyrosine protein kinase
UniProt Protein Name
Muscle, skeletal receptor tyrosine protein kinase
UniProt Gene Name
Musk
UniProt Synonym Gene Names
MuSK; Muscle-specific kinase receptor

NCBI Description

receptor tyrosine kinase expressed in myotomes, developing muscle and localized to the neuromuscular junction in the adult; expression is induced in response to injury or immobilization [RGD, Feb 2006]

Uniprot Description

MUSK: a receptor tyrosine kinase that is essential for the establishment and maintenance of the neuromuscular junction (NMJ). Its activation by agrin, a neuronally derived heparan-sulfate proteoglycan, and the agrin receptor (LRP4), leads to clustering of acetylcholine receptors on the postsynaptic side of the NMJ. Its activation by agrin requires Dok7, which interacts with the cytoplasmic portion of MuSK and activates its tyrosine kinase activity.

Protein type: EC 2.7.10.1; Kinase, protein; Membrane protein, integral; Musk family; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group

Research Articles on MUSK

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Product Notes

The MUSK musk (Catalog #AAA2074321) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FITC-Linked Polyclonal Antibody to Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (ELISA). Researchers should empirically determine the suitability of the MUSK musk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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