Rabbit anti-Human MTUS2 Polyclonal Antibody | anti-MTUS2 antibody

MTUS2, CT (Microtubule-associated Tumor Suppressor Candidate 2, Cardiac Zipper Protein, Microtubule Plus-end Tracking Protein TIP150, Tracking Protein of 150kD, CAZIP, KIAA0774, TIP150)

Cat. Num. AAA646724

• Gene Names: MTUS2; ICIS; CAZIP; TIP150; KIAA0774
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: MTUS2; Polyclonal Antibody; CT (Microtubule-associated Tumor Suppressor Candidate 2; Cardiac Zipper Protein; Microtubule Plus-end Tracking Protein TIP150; Tracking Protein of 150kD; CAZIP; KIAA0774; TIP150); Anti -MTUS2; anti-MTUS2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human MTUS2. Species sequence homology: Mouse
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.02% sodium azide.

• Applicable Applications for anti-MTUS2 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: Western Blot: 1-2ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
• Immunogen: Synthetic peptide corresponding to human MTUS2 at C-terminal conjugated to KLH.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Pancreas: Formalin- Fixed, Paraffin-Embedded (FFPE))

Related Product Information for anti-MTUS2 antibody

Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.

Product Categories/Family for anti-MTUS2 antibody

Antibodies; Abs to Microtubule-associated Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 140161498
• NCBI GeneID: 23281
• NCBI Accession #: NP_001028774.2
• NCBI GenBank Nucleotide #: NM_001033602.2
• UniProt Accession #: Q5JR59; O94872; Q08E97; Q5JQR3; Q8N5E2; A7E292; B4DF81
• Molecular Weight: 150,195 Da
• NCBI Official Full Name: microtubule-associated tumor suppressor candidate 2 isoform a
• NCBI Official Synonym Full Names: microtubule associated tumor suppressor candidate 2
• NCBI Official Symbol: MTUS2
• NCBI Official Synonym Symbols: ICIS; CAZIP; TIP150; KIAA0774
• NCBI Protein Information: microtubule-associated tumor suppressor candidate 2; +TIP of 150 kDa; cardiac zipper protein; tracking protein of 150 kDa; microtubule plus-end tracking protein TIP150
• UniProt Protein Name: Microtubule-associated tumor suppressor candidate 2
• Protein Family: Microtubule-associated tumor suppressor candidate
• UniProt Gene Name: MTUS2
• UniProt Synonym Gene Names: CAZIP; KIAA0774; TIP150; Tracking protein of 150 kDa
• UniProt Entry Name: MTUS2_HUMAN

Uniprot Description

Function: Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip. Ref.7

Subunit structure: Homodimer. Interacts with KIF2C and MAPRE1; the interaction is direct and probably targets MTUS2 and KIF2C to microtubules. Ref.7

Subcellular location: Cytoplasm › cytoskeleton. Note: Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules. Ref.7

Tissue specificity: Detected in embryonic stem cells differentiating to cardiomyocytes. Ref.6

Sequence similarities: In the C-terminal section; belongs to the MTUS1 family.

Sequence caution: The sequence AAI50246.1 differs from that shown. Reason: Erroneous initiation. The sequence BAA34494.2 differs from that shown. Reason: Erroneous initiation. The sequence CAI39910.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI39912.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI40386.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI40565.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI40566.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI41204.1 differs from that shown. Reason: Erroneous gene model prediction.