Rabbit anti-Human MTO1 Polyclonal Antibody | anti-mto1 antibody

MTO1, CT (Mitochondrial Translation Optimization 1 Homolog, CGI-02)

Cat. Num. AAA6004520

• Gene Names: mto1; mbo1; mod20
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: MTO1; Polyclonal Antibody; CT (Mitochondrial Translation Optimization 1 Homolog; CGI-02); Anti -MTO1; anti-mto1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human MTO1.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.01% sodium azide, 50% glycerol.

• Applicable Applications for anti-mto1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: ELISA: 1ug/ml; Western Blot: 1ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
• Immunogen: Synthetic peptide corresponding to human MTO1 at C-terminal (KLH).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with MTO1 antibody at 20ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody alkaline phosphatase-streptavidin and chromogen.)

Related Product Information for anti-mto1 antibody

Involved in the 5-carboxymethylaminomethyl modification (mnm5s2U34) of the wobble uridine base in mitochondrial tRNAs.

Product Categories/Family for anti-mto1 antibody

Antibodies; Abs to Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 19075784
• NCBI GeneID: 2539467
• NCBI Accession #: NP_588284.1
• NCBI GenBank Nucleotide #: NM_001023274.2
• UniProt Accession #: O94488
• Molecular Weight: 128,469 Da
• NCBI Official Full Name: MT organizer Mto1
• NCBI Official Symbol: mto1
• NCBI Official Synonym Symbols: mbo1; mod20
• NCBI Protein Information: MT organizer Mto1
• UniProt Protein Name: Microtubule organizer protein 1
• Protein Family: Mitochondrial translation optimization protein
• UniProt Gene Name: mbo1
• UniProt Synonym Gene Names: mod20; mto1
• UniProt Entry Name: MBO1_SCHPO

Uniprot Description

Function: Required for cytoplasmic astral microtubule growth during mitosis. Involved in localizing components of the gamma-tubulin complex to the non-spindle pole body (non-SPB) microtubule organizing centers (MTOCs). Required for new microtubule nucleation from non-SPB sites during interphase. Ref.1 Ref.3

Subunit structure: Interacts with mcp6. Ref.1

Subcellular location: Cytoplasm › cytoskeleton › microtubule organizing center › spindle pole body. Note: Localizes at the interphase MTOC (iMTOC) and at the equatorial MTOC (eMTOC) at the end of mitosis. Ref.1 Ref.3 Ref.4