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Rabbit MTG16 Polyclonal Antibody | anti-MTG16 antibody

MTG16 antibody

Applications
Immunohistochemistry, ELISA
Synonyms
MTG16; Polyclonal Antibody; MTG16 antibody; Polyclonal MTG16; Anti-MTG16; Core Binding Factor Runt Domain Alpha Subunit 2; Cbfa2T3; Eto2; Mtg16; Mtgr2; ZMYND4; anti-MTG16 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
MTG16 antibody detects endogenous levels of total MTG16 protein
Form/Format
Purified IgG supplied in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
459
Applicable Applications for anti-MTG16 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:20000
Biological Significance
MTG16 interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification.
Cross-Reactivity
Mouse
Immunogen
MTG16 antibody was raised in Rabbit using synthesized peptide derived from internal of human MTG16 as the immunogen
Preparation and Storage
Store in small aliquots at -20 degree C. Avoid repeated freeze/thaw cycles
Related Product Information for anti-MTG16 antibody
Rabbit polyclonal MTG16 antibody
Product Categories/Family for anti-MTG16 antibody

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
7,436 Da
NCBI Official Full Name
MTG16
UniProt Protein Name
Protein CBFA2T3
UniProt Gene Name
CBFA2T3
UniProt Synonym Gene Names
MTG16; MTGR2; ZMYND4; hMTG16
UniProt Entry Name
MTG16_HUMAN

Uniprot Description

CBFA2T3: a transcriptional repressor encoded by a gene on chromosome arm 16q, the second most frequent target of loss of heterozygosity in breast cancer. May have tumour suppressor activity. Interacts with ZNF652, a novel zinc finger protein, to repress transcription.

Protein type: Transcription, coactivator/corepressor; Nucleolus

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: Golgi membrane; nucleoplasm; nucleolus; nucleus

Molecular Function: protein binding; metal ion binding; chromatin binding; transcription factor activity; transcription corepressor activity

Biological Process: cell proliferation; transcription, DNA-dependent; granulocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent

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Product Notes

The MTG16 cbfa2t3 (Catalog #AAA839967) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MTG16 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:20000. Researchers should empirically determine the suitability of the MTG16 cbfa2t3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MTG16, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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