Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse adrenal gland tissue lysate, Primary antibody: 820978(MT2A Antibody) at dilution 1/1600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 20 seconds)
Rabbit anti-Human, Mouse MT2A Polyclonal Antibody | anti-MT2A antibody
MT2A Rabbit pAb
Gene Names
MT2A; MT2
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
MT2A; Polyclonal Antibody; MT2A Rabbit pAb; metallothionein 2A; MT2; MT-2; MT-II; anti-MT2A antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-MT2A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:1000-1:5000
ELISA: 1:5000-1:10,000
IHC: 1:50-1:300
ELISA: 1:5000-1:10,000
IHC: 1:50-1:300
Immunogen
Fusion protein of human MT2A
Conjugation
Unconjugated
Molecular Function
Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.MiscellaneousThis metallothionein binds zinc.SitesFeature keyPosition(s)Description
Modification
Unmodified
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse adrenal gland tissue lysate, Primary antibody: 820978(MT2A Antibody) at dilution 1/1600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 20 seconds)
Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse adrenal gland tissue lysate, Primary antibody: 820978(MT2A Antibody) at dilution 1/1600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 20 seconds)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 820978(MT2A Antibody) at dilution 1/70. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 820978(MT2A Antibody) at dilution 1/70. (Original magnification: ×200))
Related Product Information for anti-MT2A antibody
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions, altering the intracellular concentration of heavy metals in the cell. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. The encoded protein interacts with the protein encoded by the homeobox containing 1 gene in some cell types, controlling intracellular zinc levels, affecting apoptotic and autophagy pathways. Some polymorphisms in this gene are associated with an increased risk of cancer.
Product Categories/Family for anti-MT2A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
6,042 Da
NCBI Official Full Name
Metallothionein 2
NCBI Official Synonym Full Names
metallothionein 2A
NCBI Official Symbol
MT2A
NCBI Official Synonym Symbols
MT2
NCBI Protein Information
metallothionein-2; MT-2; MT-II; metallothionein-2A; metallothionein-II
UniProt Protein Name
Metallothionein-2
Protein Family
UniProt Gene Name
MT2A
UniProt Synonym Gene Names
CES1; MT2; MT-2; MT-II
UniProt Entry Name
MT2_HUMAN
Uniprot Description
MT2A: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. Belongs to the metallothionein superfamily. Type 1 family.
Protein type: Carrier
Chromosomal Location of Human Ortholog: 16q13
Cellular Component: perinuclear region of cytoplasm; cytoplasm; nucleus; cytosol
Molecular Function: protein binding; zinc ion binding; drug binding
Biological Process: cellular copper ion homeostasis; cytokine and chemokine mediated signaling pathway; negative regulation of growth
Research Articles on MT2A
Similar Products
Product Notes
The MT2A mt2a (Catalog #AAA4757822) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MT2A Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MT2A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:1000-1:5000 ELISA: 1:5000-1:10,000 IHC: 1:50-1:300. Researchers should empirically determine the suitability of the MT2A mt2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MT2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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