Rabbit anti-Human MT-ATP8 Polyclonal Antibody | anti-MT-ATP8 antibody

MT-ATP8 Antibody

Cat. Num. AAA9609557

• Gene Names: MT-ATP8; ATPase8; MTATP8; ATP8
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Peptide affinity purification
• Synonyms: MT-ATP8; Polyclonal Antibody; MT-ATP8 Antibody; anti-MT-ATP8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: MT-ATP8 antibody detects endogenous levels of total MT-ATP8
• Purity/Purification: Peptide affinity purification
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 68

• Applicable Applications for anti-MT-ATP8 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:1000-3000; ELISA(peptide): 1:20000-1:40000; ; The optimal dilutions should be determined by the end user.
• Immunogen: A synthesized peptide derived from human MT-ATP8, corresponding to a region within internal amino acids.
• Preparation and Storage: Store at -20°C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of MT-ATP8 using Jurkat whole cell lysates)

Related Product Information for anti-MT-ATP8 antibody

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1-containing the extramembraneous catalytic core and F0-containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane (By similarity).
Subunit Structure: F-type ATPases have 2 components, CF1-the catalytic core-and CF0-the membrane proton channel. Component of an ATP synthase complex composed of ATP5F1, ATP5MC1, ATP5F1E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5O, ATP5L, USMG5 and MP68 (By similarity).
Similarity: Belongs to the ATPase protein 8 family.

NCBI and Uniprot Product Information

• NCBI GI #: 251831111
• NCBI GeneID: 4509
• NCBI Accession #: YP_003024030.1
• NCBI GenBank Nucleotide #: NC_012920.1
• UniProt Accession #: P03928; Q34771
• Molecular Weight: 8 kDa
• NCBI Official Full Name: ATP synthase F0 subunit 8 (mitochondrion)
• NCBI Official Synonym Full Names: mitochondrially encoded ATP synthase 8
• NCBI Official Symbol: MT-ATP8
• NCBI Official Synonym Symbols: ATPase8; MTATP8; ATP8
• NCBI Protein Information: ATP synthase F0 subunit 8
• UniProt Protein Name: ATP synthase protein 8
• UniProt Gene Name: MT-ATP8
• UniProt Synonym Gene Names: ATP8; ATPASE8; MTATP8

Uniprot Description

Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane ().