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Testing Data (Primary: Anti- MST3/STK3 at 1/1000 dilution )

Rabbit MST3/STK3 Polyclonal Antibody | anti-MST3/STK3 antibody

MST3/STK3 Polyclonal Antibody

Gene Names
STK24; MST3; STK3; MST3B; STE20
Reactivity
Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
MST3/STK3; Polyclonal Antibody; MST3/STK3 Polyclonal Antibody; Kinase responsive to stress 1; KRS1; Mammalian STE20 like protein kinase 2; Mammalian sterile 20-like 2; Mess1; MST; MST-2; MST2; Mst3; Serine/threonine kinase 3 (STE20 homolog; yeast); Serine/threonine kinase 3 (Ste20; yeast homolog); Serine/threonine protein kinase 3; Serine/threonine protein kinase Krs1; STE20 like kinase MST2; anti-MST3/STK3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit
Clonality
Polyclonal
Specificity
MST3/STK3 Polyclonal Antibody detects endogenous levels of MST3/STK3 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-MST3/STK3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from human STK3:101-200/491
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Testing Data

(Primary: Anti- MST3/STK3 at 1/1000 dilution )

Testing Data (Primary: Anti- MST3/STK3 at 1/1000 dilution )

Testing Data

(Primary: Anti- MST3/STK3 at 1/20000 dilution )

Testing Data (Primary: Anti- MST3/STK3 at 1/20000 dilution )

Testing Data

(Primary: Anti- MST3/STK3 at 1/1000 dilution )

Testing Data (Primary: Anti- MST3/STK3 at 1/1000 dilution )

Testing Data

(Primary: Anti- MST3/STK3 at 1/1000 dilution )

Testing Data (Primary: Anti- MST3/STK3 at 1/1000 dilution )
Related Product Information for anti-MST3/STK3 antibody
STK3 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
49,308 Da
NCBI Official Full Name
serine/threonine-protein kinase 24 isoform b
NCBI Official Synonym Full Names
serine/threonine kinase 24
NCBI Official Symbol
STK24
NCBI Official Synonym Symbols
MST3; STK3; MST3B; STE20
NCBI Protein Information
serine/threonine-protein kinase 24; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3; mammalian STE20-like protein kinase 3; serine/threonine kinase 24 (STE20 homolog, yeast)
UniProt Protein Name
Serine/threonine-protein kinase 24
UniProt Gene Name
STK24
UniProt Synonym Gene Names
MST3; STK3; MST-3; MST3/N; MST3/C
UniProt Entry Name
STK24_HUMAN

NCBI Description

The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases (Zhou et al., 2000 [PubMed 10644707]).[supplied by OMIM, Mar 2008]

Uniprot Description

MST3: a protein kinase of the STE20 family. Activated by caspase-mediated cleavage

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; Protein kinase, STE; STE group; STE20 family; YSK subfamily

Chromosomal Location of Human Ortholog: 13q31.2-q32.3

Cellular Component: nucleoplasm; membrane; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function: protein serine/threonine kinase activity; protein binding; metal ion binding; ATP binding; receptor signaling protein serine/threonine kinase activity; protein kinase activity

Biological Process: regulation of axon regeneration; response to hydrogen peroxide; apoptosis; protein amino acid autophosphorylation; signal transduction; negative regulation of cell migration; protein amino acid phosphorylation; induction of apoptosis by oxidative stress; cell structure disassembly during apoptosis

Research Articles on MST3/STK3

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Product Notes

The MST3/STK3 stk24 (Catalog #AAA3015516) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MST3/STK3 Polyclonal Antibody reacts with Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's MST3/STK3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the MST3/STK3 stk24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MST3/STK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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