Rabbit anti-Human MS4A7 Polyclonal Antibody | anti-MS4A7 antibody

MS4A7, ID (MS4A7, 4SPAN2, CD20L4, CFFM4, Membrane-spanning 4-domains subfamily A member 7, CD20 antigen-like 4, CD20/FC-epsilon-RI-beta family member 4, Four-span transmembrane protein 2) (AP)

Cat. Num. AAA6322439

• Gene Names: MS4A7; CFFM4; MS4A8; 4SPAN2; CD20L4
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MS4A7; Polyclonal Antibody; ID (MS4A7; 4SPAN2; CD20L4; CFFM4; Membrane-spanning 4-domains subfamily A member 7; CD20 antigen-like 4; CD20/FC-epsilon-RI-beta family member 4; Four-span transmembrane protein 2) (AP); Four-span transmembrane protein 2; anti-MS4A7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
• Sequence Length: 195

• Applicable Applications for anti-MS4A7 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: MS4A7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the Central region of human MS4A7.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(MS4A7 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MS4A7 antibody detected the MS4A7 protein (arrow).)

Related Product Information for anti-MS4A7 antibody

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq].

Product Categories/Family for anti-MS4A7 antibody

Antibodies; Transmembrane Proteins

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Gingras, M.C., et al. Immunogenetics 53(6):468-476(2001). Liang, Y., et al. Immunogenetics 53(5):357-368(2001). Liang, Y., et al. Genomics 72(2):119-127(2001). Ishibashi, K., et al. Gene 264(1):87-93(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 46249347
• NCBI GeneID: 58475
• NCBI Accession #: NP_996821.1; NP_996823.1
• NCBI GenBank Nucleotide #: NP_996821.1
• UniProt Accession #: Q9GZW8
• NCBI Official Full Name: membrane-spanning 4-domains subfamily A member 7 isoform 2
• NCBI Official Synonym Full Names: membrane spanning 4-domains A7
• NCBI Official Symbol: MS4A7
• NCBI Official Synonym Symbols: CFFM4; MS4A8; 4SPAN2; CD20L4
• NCBI Protein Information: membrane-spanning 4-domains subfamily A member 7
• UniProt Protein Name: Membrane-spanning 4-domains subfamily A member 7
• Protein Family: Membrane-spanning 4-domains subfamily
• UniProt Gene Name: MS4A7
• UniProt Synonym Gene Names: 4SPAN2; CD20L4; CFFM4
• UniProt Entry Name: MS4A7_HUMAN

NCBI Description

This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Uniprot Description

MS4A7: May be involved in signal transduction as a component of a multimeric receptor complex. Belongs to the MS4A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: integral to membrane