Rabbit anti-Human MS4A6A Polyclonal Antibody | anti-MS4A6A antibody

MS4A6A, NT (MS4A6A, 4SPAN3, CD20L3, MS4A6, Membrane-spanning 4-domains subfamily A member 6A, CD20 antigen-like 3, Four-span transmembrane protein 3) (FITC)

Cat. Num. AAA6322431

• Gene Names: MS4A6A; CDA01; MS4A6; 4SPAN3; CD20L3; MST090; MSTP090; 4SPAN3.2
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A and Peptide Affinity Chromatography.
• Synonyms: MS4A6A; Polyclonal Antibody; NT (MS4A6A; 4SPAN3; CD20L3; MS4A6; Membrane-spanning 4-domains subfamily A member 6A; CD20 antigen-like 3; Four-span transmembrane protein 3) (FITC); Four-span transmembrane protein 3; anti-MS4A6A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human MS4A6A.
• Purity/Purification: Purified by Protein A and Peptide Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-MS4A6A antibody: Western Blot (WB), FLISA
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 11-38 in the N-terminal region of human MS4A6A, UniProt Accession #Q9H2W1, Q96DS6
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis in 293 cell line lysates (35ug/lane) usingMBS6008443. This demonstrates MBS6008443 detected the MS4A6A protein (arrow).)

Related Product Information for anti-MS4A6A antibody

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.1, among a cluster of family members. Alternative splicing of this gene results in several transcript variants.

Product Categories/Family for anti-MS4A6A antibody

Antibodies; Transmembrane Proteins

References

Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010). Davila, S., et al. Genes Immun. 11(3):232-238(2010). Liang, Y., et al. Immunogenetics 53(5):357-368(2001). Liang, Y., et al. Genomics 72(2):119-127(2001). Ishibashi, K., et al. Gene 264(1):87-93(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 23238234
• NCBI GeneID: 64231
• NCBI Accession #: NP_071744.2
• NCBI GenBank Nucleotide #: NM_022349.3
• UniProt Accession #: Q9H2W1; Q7Z4E8; Q8TBV7; Q8TEZ4; Q8TEZ5; Q96PG6; Q9H2L1; Q9H2N3; Q9H3V1; Q9HC76; A8K755; F8W9K1
• Molecular Weight: 27,438 Da
• NCBI Official Full Name: membrane-spanning 4-domains subfamily A member 6A isoform 2
• NCBI Official Synonym Full Names: membrane-spanning 4-domains, subfamily A, member 6A
• NCBI Official Symbol: MS4A6A
• NCBI Official Synonym Symbols: CDA01; MS4A6; 4SPAN3; CD20L3; MST090; MSTP090; 4SPAN3.2
• NCBI Protein Information: membrane-spanning 4-domains subfamily A member 6A; HAIRB-iso; MS4A6A-polymorph; CD20-like precusor; CD20 antigen-like 3; four-span transmembrane protein 3; four-span transmembrane protein 3.1; four-span transmembrane protein 3.2; membrane-spanning 4-domai
• UniProt Protein Name: Membrane-spanning 4-domains subfamily A member 6A
• Protein Family: Membrane-spanning 4-domains subfamily
• UniProt Gene Name: MS4A6A
• UniProt Synonym Gene Names: 4SPAN3; CD20L3; MS4A6
• UniProt Entry Name: M4A6A_HUMAN

NCBI Description

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.1, among a cluster of family members. Alternative splicing of this gene results in several transcript variants that encode different protein isoforms. [provided by RefSeq, Oct 2011]

Uniprot Description

MS4A6A: May be involved in signal transduction as a component of a multimeric receptor complex. Belongs to the MS4A family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: integral to membrane