Rabbit anti-Mouse MRPS2 Polyclonal Antibody | anti-MRPS2 antibody

MRPS2 Polyclonal Antibody

Cat. Num. AAA3010051

• Gene Names: MRPS2; S2mt; CGI-91; MRP-S2; COXPD36
• Reactivity: Mouse
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: MRPS2; Polyclonal Antibody; MRPS2 Polyclonal Antibody; CGI-91; MRP-S2; S2mt; anti-MRPS2 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: MRPS2 polyclonal antibody detects endogenous levels of MRPS2 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 296

• Applicable Applications for anti-MRPS2 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant protein of human MRPS2
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cell lines, using MRPS2 antibody at 1:3000 dilution.)

Related Product Information for anti-MRPS2 antibody

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 7705805
• NCBI GeneID: 51116
• NCBI Accession #: NP_057118.1
• NCBI GenBank Nucleotide #: NP_057118.1
• UniProt Accession #: Q9Y399
• Molecular Weight: 33kDa
• NCBI Official Full Name: 28S ribosomal protein S2, mitochondrial
• NCBI Official Synonym Full Names: mitochondrial ribosomal protein S2
• NCBI Official Symbol: MRPS2
• NCBI Official Synonym Symbols: S2mt; CGI-91; MRP-S2; COXPD36
• NCBI Protein Information: 28S ribosomal protein S2, mitochondrial
• UniProt Protein Name: 28S ribosomal protein S2, mitochondrial
• Protein Family: 28S ribosomal protein
• UniProt Gene Name: MRPS2
• UniProt Synonym Gene Names: MRP-S2; S2mt
• UniProt Entry Name: RT02_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Uniprot Description

MRPS2: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Protein type: Ribosomal; Translation; Mitochondrial

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: mitochondrion; mitochondrial small ribosomal subunit

Molecular Function: structural constituent of ribosome

Biological Process: translation