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Western Blot (WB) (Western blot analysis of extracts from K562 cells, using MRPS18C antibody.)

Rabbit anti-Human, Mouse MRPS18C Polyclonal Antibody | anti-MRPS18C antibody

MRPS18C Antibody

Gene Names
MRPS18C; CGI-134; MRPS18-1; MRP-S18-1
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MRPS18C; Polyclonal Antibody; MRPS18C Antibody; 28S ribosomal protein S18c; mitochondrial; MRP-S18-1; MRP-S18-c; RT18C; anti-MRPS18C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; Rabbit IgG In Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Applicable Applications for anti-MRPS18C antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:3000
IHC: 1:50-1:100
IF: 1:100-1:500
Immunogen
Synthesized peptide derived from internal of human MRPS18C.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blot analysis of extracts from K562 cells, using MRPS18C antibody.)

Western Blot (WB) (Western blot analysis of extracts from K562 cells, using MRPS18C antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using MRPS18C antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using MRPS18C antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of MCF-7 cells, using MRPS18C antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of MCF-7 cells, using MRPS18C antibody.)
Product Categories/Family for anti-MRPS18C antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15,850 Da
NCBI Official Full Name
28S ribosomal protein S18c, mitochondrial
NCBI Official Synonym Full Names
mitochondrial ribosomal protein S18C
NCBI Official Symbol
MRPS18C
NCBI Official Synonym Symbols
CGI-134; MRPS18-1; MRP-S18-1
NCBI Protein Information
28S ribosomal protein S18c, mitochondrial; S18mt-c; mrps18-c; MRP-S18-c; mitochondrial ribosomal protein S18-1; 28S ribosomal protein S18-1, mitochondrial
UniProt Protein Name
28S ribosomal protein S18c, mitochondrial
Protein Family
UniProt Gene Name
MRPS18C
UniProt Synonym Gene Names
MRP-S18-c; Mrps18-c; S18mt-c; MRP-S18-1
UniProt Entry Name
RT18C_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPS18C: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008]

Protein type: Ribosomal; Translation; Mitochondrial

Chromosomal Location of Human Ortholog: 4q21.23

Cellular Component: mitochondrial small ribosomal subunit; mitochondrial inner membrane

Molecular Function: structural constituent of ribosome

Biological Process: translation; mitochondrial translation; organelle organization and biogenesis

Research Articles on MRPS18C

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Product Notes

The MRPS18C mrps18c (Catalog #AAA7132805) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRPS18C Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MRPS18C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:3000 IHC: 1:50-1:100 IF: 1:100-1:500. Researchers should empirically determine the suitability of the MRPS18C mrps18c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRPS18C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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