Rabbit anti-Human MRPL50 Polyclonal Antibody | anti-MRPL50 antibody

MRPL50 Antibody

Cat. Num. AAA9407031

• Gene Names: MRPL50; MRP-L50
• Reactivity: Human
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: MRPL50; Polyclonal Antibody; MRPL50 Antibody; flj20493; flj21990; mitochondrial ribosomal protein l50; mrp-l50; mrpl50; anti-MRPL50 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total MRPL50 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 158

• Applicable Applications for anti-MRPL50 antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:500~1:3000
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from internal of human MRPL50.
• Target Name: MRPL50
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from COLO cells and HT-29 cells, using MRPL50 antibody.)

Related Product Information for anti-MRPL50 antibody

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.Ota T., Nat. Genet. 36:40-45(2004).Humphray S.J., Nature 429:369-374(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Product Categories/Family for anti-MRPL50 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 21265096
• NCBI GeneID: 54534
• NCBI Accession #: NP_061924.1
• NCBI GenBank Nucleotide #: NM_019051.2
• UniProt Accession #: Q8N5N7; Q5T7E0; Q9NX15; B7Z358
• Molecular Weight: 15,524 Da
• NCBI Official Full Name: 39S ribosomal protein L50, mitochondrial
• NCBI Official Synonym Full Names: mitochondrial ribosomal protein L50
• NCBI Official Symbol: MRPL50
• NCBI Official Synonym Symbols: MRP-L50
• NCBI Protein Information: 39S ribosomal protein L50, mitochondrial
• UniProt Protein Name: 39S ribosomal protein L50, mitochondrial
• Protein Family: 39S ribosomal protein
• UniProt Gene Name: MRPL50
• UniProt Synonym Gene Names: L50mt; MRP-L50
• UniProt Entry Name: RM50_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPL50: 2 isoforms of the human protein are produced by alternative splicing

Chromosomal Location of Human Ortholog: 9q31.1

Cellular Component: mitochondrial inner membrane; ribosome

Biological Process: mitochondrial translation; organelle organization and biogenesis