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Western Blot (WB) (Western blot analysis of extracts of various cell lines using MRPL2 Polyclonal Antibody at dilution of 1:1000.)

Rabbit anti-Human, Mouse MRPL2 Polyclonal Antibody | anti-MRPL2 antibody

MRPL2 Polyclonal Antibody

Gene Names
MRPL2; CGI-22; RPML14; MRP-L14
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity purification
Synonyms
MRPL2; Polyclonal Antibody; MRPL2 Polyclonal Antibody; CGI-22; MRP-L14; RPML14; anti-MRPL2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-MRPL2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human MRPL2 (NP_0570342)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines using MRPL2 Polyclonal Antibody at dilution of 1:1000.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines using MRPL2 Polyclonal Antibody at dilution of 1:1000.)
Related Product Information for anti-MRPL2 antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Product Categories/Family for anti-MRPL2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33,301 Da
NCBI Official Full Name
39S ribosomal protein L2, mitochondrial isoform 2
NCBI Official Synonym Full Names
mitochondrial ribosomal protein L2
NCBI Official Symbol
MRPL2
NCBI Official Synonym Symbols
CGI-22; RPML14; MRP-L14
NCBI Protein Information
39S ribosomal protein L2, mitochondrial
UniProt Protein Name
39S ribosomal protein L2, mitochondrial
Protein Family
UniProt Gene Name
MRPL2
UniProt Synonym Gene Names
L2mt; MRP-L2
UniProt Entry Name
RM02_HUMAN

Uniprot Description

MRPL2: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. [provided by RefSeq, Jul 2008]

Protein type: Mitochondrial; Motility/polarity/chemotaxis; RNA-binding; Ribosomal; Translation

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: mitochondrial inner membrane; mitochondrial large ribosomal subunit

Molecular Function: structural constituent of ribosome

Biological Process: mitochondrial translation

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Product Notes

The MRPL2 mrpl2 (Catalog #AAA2565112) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRPL2 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MRPL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MRPL2 mrpl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRPL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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