Rabbit MRPL11 Polyclonal Antibody | anti-MRPL11 antibody

MRPL11 Antibody

Cat. Num. AAA7125970

• Gene Names: MRPL11; L11MT; CGI-113; MRP-L11
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purification
• Synonyms: MRPL11; Polyclonal Antibody; MRPL11 Antibody; mitochondrial ribosomal protein L11; anti-MRPL11 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol

• Applicable Applications for anti-MRPL11 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: ELISA: 1:2000-1:5000; WB: 1:500-1:2000; IHC: 1:50-1:200
• Immunogen: Fusion protein of human MRPL11
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using MBS7125970(MRPL11 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using MBS7125970(MRPL11 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200))

SDS-Page

(Gel: 10%SDS-PAGE, Lysate: 40 ug, Lane 1-5: Jurkat cells, K562 cells, lncap cells, hepg2 cells, hela cells, Primary antibody: MBS7125970(MRPL11 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds)

Product Categories/Family for anti-MRPL11 antibody

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 7705618
• NCBI GeneID: 65003
• NCBI Accession #: NP_057134.1
• NCBI GenBank Nucleotide #: NM_016050.3
• UniProt Accession #: Q9Y3B7; Q32P46; Q96Q73; A6NLT0; A8K219
• Molecular Weight: 20,683 Da
• NCBI Official Full Name: 39S ribosomal protein L11, mitochondrial isoform a
• NCBI Official Synonym Full Names: mitochondrial ribosomal protein L11
• NCBI Official Symbol: MRPL11
• NCBI Official Synonym Symbols: L11MT; CGI-113; MRP-L11
• NCBI Protein Information: 39S ribosomal protein L11, mitochondrial
• UniProt Protein Name: 39S ribosomal protein L11, mitochondrial
• Protein Family: 39S ribosomal protein
• UniProt Gene Name: MRPL11
• UniProt Synonym Gene Names: L11mt; MRP-L11
• UniProt Entry Name: RM11_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPL11: Belongs to the ribosomal protein L11P family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Mitochondrial

Chromosomal Location of Human Ortholog: 11q13.3

Cellular Component: mitochondrial inner membrane; mitochondrial ribosome

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: translation; mitochondrial translation; organelle organization and biogenesis