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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using MRM3 antibody.)

Rabbit anti-Human MRM3 Polyclonal Antibody | anti-MRM3 antibody

MRM3 Polyclonal Antibody

Gene Names
MRM3; RMTL1; RNMTL1
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purification
Synonyms
MRM3; Polyclonal Antibody; MRM3 Polyclonal Antibody; 16S rRNA (guanosine(1370)-2'-O)-methyltransferase; 16S rRNA [Gm1370] 2'-O-methyltransferase; 4833420N02Rik; AI255153; FLJ10581; HC90; Putative RNA methyltransferase; RMTL1; RNA methyltransferase like 1; RNA methyltransferase like protein 1; RNA methyltransferase-like protein 1; RP23-147P4.7; rRNA methyltransferase 3; mitochondrial; anti-MRM3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration
1 mg/mL (varies by lot)
Sequence Length
420
Applicable Applications for anti-MRM3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human MRM3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using MRM3 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using MRM3 antibody.)
Related Product Information for anti-MRM3 antibody
Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-MRM3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 47kDa
Observed: 47kDa
NCBI Official Full Name
rRNA methyltransferase 3, mitochondrial isoform 2
NCBI Official Synonym Full Names
mitochondrial rRNA methyltransferase 3
NCBI Official Symbol
MRM3
NCBI Official Synonym Symbols
RMTL1; RNMTL1
NCBI Protein Information
rRNA methyltransferase 3, mitochondrial
UniProt Protein Name
rRNA methyltransferase 3, mitochondrial
Protein Family
UniProt Gene Name
MRM3

NCBI Description

Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

Uniprot Description

S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.

Research Articles on MRM3

Similar Products

Product Notes

The MRM3 mrm3 (Catalog #AAA2555872) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRM3 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MRM3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MRM3 mrm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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