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Western Blot (WB) (Western blot analysis of MOSC2 Antibody (C-term) in Hela cell line lysates (35ug/lane). MOSC2 (arrow) was detected using the purified Pab.)

Rabbit anti-Human MOSC2 Polyclonal Antibody | anti-MOSC2 antibody

MOSC2, CT (MOSC Domain-containing Protein 2 Mitochondrial, FLJ20605, RP11-270A6.1) (APC)

Gene Names
MOSC2; FLJ20605; RP11-270A6.1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Immunoaffinity chromatography.
Synonyms
MOSC2; Polyclonal Antibody; CT (MOSC Domain-containing Protein 2 Mitochondrial; FLJ20605; RP11-270A6.1) (APC); MOCO Sulphurase C-terminal Domain Containing 2; EC=1.-.-.-; anti-MOSC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human MOSC2.
Purity/Purification
Purified by Immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-MOSC2 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the C-terminal region of human MOSC2 (KLH).
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of MOSC2 Antibody (C-term) in Hela cell line lysates (35ug/lane). MOSC2 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of MOSC2 Antibody (C-term) in Hela cell line lysates (35ug/lane). MOSC2 (arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MOSC2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MOSC2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(MOSC2 Antibody (C-term) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (MOSC2 Antibody (C-term) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Western Blot (WB)

(Western blot analysis of MOSC2 (arrow) using rabbit polyclonal MOSC2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOSC2 gene.)

Western Blot (WB) (Western blot analysis of MOSC2 (arrow) using rabbit polyclonal MOSC2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOSC2 gene.)
Product Categories/Family for anti-MOSC2 antibody
References
1. Havemeyer, A., et.al., J. Biol. Chem. 281(46), 34796-34802 (2006). 2. Simpson, J.C., et.al., EMBO Rep. 1(3), 287-292 (2000).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,023 Da
NCBI Official Full Name
MOSC domain-containing protein 2, mitochondrial
NCBI Official Synonym Full Names
MOCO sulphurase C-terminal domain containing 2
NCBI Official Symbol
MOSC2
NCBI Official Synonym Symbols
FLJ20605; RP11-270A6.1
NCBI Protein Information
MOSC domain-containing protein 2, mitochondrial; OTTHUMP00000035465
UniProt Protein Name
MOSC domain-containing protein 2, mitochondrial
UniProt Gene Name
MOSC2
UniProt Entry Name
MOSC2_HUMAN

Uniprot Description

MOSC2: As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.-.-.-; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; peroxisome

Molecular Function: molybdopterin cofactor binding; nitrate reductase activity; molybdenum ion binding; pyridoxal phosphate binding

Biological Process: detoxification of nitrogen compound; nitrate metabolic process

Research Articles on MOSC2

Similar Products

Product Notes

The MOSC2 mosc2 (Catalog #AAA6488534) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MOSC2, CT (MOSC Domain-containing Protein 2 Mitochondrial, FLJ20605, RP11-270A6.1) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MOSC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-1:500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MOSC2 mosc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MOSC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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