Rabbit Mortality Factor 4 Polyclonal Antibody | anti-MORF4 antibody
Mortality Factor 4 (MORF4, CSR, SEN, CSRB, SEN1)
Gene Names
MORF4; CSR; SEN; CSRB; SEN1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Mortality Factor 4; Polyclonal Antibody; Mortality Factor 4 (MORF4; CSR; SEN; CSRB; SEN1); Anti -Mortality Factor 4 (MORF4; anti-MORF4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human MORF4. Species Crossreactivity: mouse, rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-MORF4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in Immunohistochemistry (paraffin) and Western Blot.
Dilution: Immunohistochemistry (paraffin): 5ug/ml
Western Blot: 1ug/ml
Dilution: Immunohistochemistry (paraffin): 5ug/ml
Western Blot: 1ug/ml
Immunogen
A peptide corresponding to an 18aa peptide from near the amino terminus of human MORF4.
Positive Control
Human brain tissue
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-MORF4 antibody
Mortality Factor 4 (MORF4), known also as SEN1 and cellular senescence-related protein 1. MORF4 is a nuclear localized protein possessing transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that are believed to allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription co-repressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
Product Categories/Family for anti-MORF4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
mortality factor 4 [Homo sapiens]
NCBI Official Synonym Full Names
mortality factor 4
NCBI Official Symbol
MORF4
NCBI Official Synonym Symbols
CSR; SEN; CSRB; SEN1
NCBI Protein Information
mortality factor 4; senescence (cellular)-related 1; senescence-related, cellular, 1
Protein Family
NCBI Description
Cellular senescence, the terminal nondividing state that normal cells enter following completion of their proliferative potential, is the dominant phenotype in hybrids of normal and immortal cells. Fusions of immortal human cell lines with each other have led to their assignment to 1 of several complementation groups. MORF4 is a gene on chromosome 4 that induces a senescent-like phenotype in cell lines assigned to complementation group B.[supplied by OMIM]
Research Articles on MORF4
Similar Products
Product Notes
The MORF4 (Catalog #AAA621511) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mortality Factor 4 (MORF4, CSR, SEN, CSRB, SEN1) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Mortality Factor 4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in Immunohistochemistry (paraffin) and Western Blot. Dilution: Immunohistochemistry (paraffin): 5ug/ml Western Blot: 1ug/ml. Researchers should empirically determine the suitability of the MORF4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mortality Factor 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
