Western Blot (WB)
(Anti- MMP3 Picoband antibody, MBS177674, Western blottingAll lanes: Anti MMP3 (MBS177674) at 0.5ug/mlWB: Recombinant Human MMP3 Protein 0.5ngPredicted bind size: 36KDObserved bind size: 36KD )
anti-Human MMP3 Polyclonal Antibody | anti-MMP3 antibody
Anti-MMP3 Antibody
Western Blot (WB)
(Anti- MMP3 Picoband antibody, MBS177674, Western blottingAll lanes: Anti MMP3 (MBS177674) at 0.5ug/mlWB: Recombinant Human MMP3 Protein 0.5ngPredicted bind size: 36KDObserved bind size: 36KD )
Western Blot (WB)
(Anti- MMP3 Picoband antibody, MBS177674, Western blottingAll lanes: Anti MMP3 (MBS177674) at 0.5ug/mlWB: Recombinant Human MMP3 Protein 0.5ngPredicted bind size: 36KDObserved bind size: 36KD )
Western Blot (WB)
(Anti- MMP3 Picoband antibody, MBS177674, Western blottingAll lanes: Anti MMP3 (MBS177674) at 0.5ug/mlLane 1: Human Placenta Tissue Lysate at 50ugLane 2: U20S Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: PANC Whole Cell Lysate at 40ugLane 5: COLO320 Whole Cell Lysate at 40ugPredicted bind size: 54KDObserved bind size: 54KD )
Western Blot (WB)
(Anti- MMP3 Picoband antibody, MBS177674, Western blottingAll lanes: Anti MMP3 (MBS177674) at 0.5ug/mlLane 1: Human Placenta Tissue Lysate at 50ugLane 2: U20S Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: PANC Whole Cell Lysate at 40ugLane 5: COLO320 Whole Cell Lysate at 40ugPredicted bind size: 54KDObserved bind size: 54KD )
Background: Stromelysin-1, also known as matrix metalloproteinase-3 (MMP-3), is an enzyme that in humans is encoded by the MMP3 gene. It is mapped to 11q22.2. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix and during tissue remodeling in normal physiological processes, such as embryonic development and reproduction, as well as in disease processes, such as arthritis, and tumour metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
NCBI and Uniprot Product Information
NCBI Description
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Uniprot Description
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Research Articles on MMP3
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Product Notes
The MMP3 mmp3 (Catalog #AAA177674) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-MMP3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MMP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot Concentration: 0.1-0.5ug/ml. Researchers should empirically determine the suitability of the MMP3 mmp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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