Knockout Validation
(Knockout Validation: Lane 1: Wild-type MCF7 cell lysate; Lane 2: MRPL1 knockout MCF7 cell lysate; Predicted MW: 37kd Observed MW: 34kd Primary Ab: 1ug/ml Rabbit Anti-Human MRPL1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Rabbit anti-Human Mitochondrial Ribosomal Protein L1 (MRPL1) Polyclonal Antibody | anti-MRPL1 antibody
Biotin-Linked Polyclonal Antibody to Mitochondrial Ribosomal Protein L1 (MRPL1)
Knockout Validation
(Knockout Validation: Lane 1: Wild-type MCF7 cell lysate; Lane 2: MRPL1 knockout MCF7 cell lysate; Predicted MW: 37kd Observed MW: 34kd Primary Ab: 1ug/ml Rabbit Anti-Human MRPL1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
Knockout Validation
(Knockout Validation: Lane 1: Wild-type MCF7 cell lysate; Lane 2: MRPL1 knockout MCF7 cell lysate; Predicted MW: 37kd Observed MW: 34kd Primary Ab: 1ug/ml Rabbit Anti-Human MRPL1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (#MBS2086047))
NCBI and Uniprot Product Information
NCBI Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
Uniprot Description
MRPL1: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
Protein type: Mitochondrial; RNA-binding
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: mitochondrial inner membrane; mitochondrion
Molecular Function: protein binding; RNA binding; structural constituent of ribosome
Biological Process: cleavage involved in rRNA processing; maturation of LSU-rRNA; rRNA pseudouridine synthesis; snRNA pseudouridine synthesis; translation
Research Articles on MRPL1
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Product Notes
The MRPL1 mrpl1 (Catalog #AAA2094732) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Biotin-Linked Polyclonal Antibody to Mitochondrial Ribosomal Protein L1 (MRPL1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Mitochondrial Ribosomal Protein L1 (MRPL1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the MRPL1 mrpl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mitochondrial Ribosomal Protein L1 (MRPL1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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