Rabbit anti-Human MIPEP Polyclonal Antibody | anti-MIPEP antibody

MIPEP Rabbit Polyclonal

Cat. Num. AAA7601428

• Gene Names: MIPEP; MIP; HMIP
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: MIPEP; Polyclonal Antibody; MIPEP Rabbit Polyclonal; anti-MIPEP antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 713

• Applicable Applications for anti-MIPEP antibody: ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
• Immunogen: Mitochondrial intermediate peptidase
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate cancer using MBS7601428 (MIPEP antibody) at dilution of 1:50)

Western Blot (WB)

(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7601428 (MIPEP antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 156105687
• NCBI GeneID: 4285
• NCBI Accession #: NP_005923.2
• NCBI GenBank Nucleotide #: NM_005932.3
• Molecular Weight: 80,641 Da
• NCBI Official Full Name: mitochondrial intermediate peptidase
• NCBI Official Synonym Full Names: mitochondrial intermediate peptidase
• NCBI Official Symbol: MIPEP
• NCBI Official Synonym Symbols: MIP; HMIP
• NCBI Protein Information: mitochondrial intermediate peptidase
• UniProt Protein Name: Mitochondrial intermediate peptidase
• Protein Family: Mitochondrial intermediate peptidase
• UniProt Gene Name: MIPEP
• UniProt Synonym Gene Names: MIP; MIP
• UniProt Entry Name: MIPEP_HUMAN

NCBI Description

The product of this gene performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This gene may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia. [provided by RefSeq, Jul 2008]

Uniprot Description

MIPEP: Cleaves proteins, imported into the mitochondrion, to their mature size. Belongs to the peptidase M3 family.

Protein type: EC 3.4.24.59; Protease; Mitochondrial

Chromosomal Location of Human Ortholog: 13q12

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: metal ion binding; metalloendopeptidase activity

Biological Process: mitochondrial protein processing; peptide metabolic process