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Rabbit MGM1 Polyclonal Antibody | anti-MGM1 antibody

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) MGM1 Polyclonal Antibody

Gene Names
MGM1; MNA1
Reactivity
Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
Applications
ELISA, Western Blot
Purity
Protein A/G
Synonyms
MGM1; Polyclonal Antibody; Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) MGM1 Polyclonal Antibody; MGM1 Antibody; Dynamin-like GTPase MGM1; mitochondrial; Mitochondrial division and morphology protein 17; Mitochondrial genome maintenance protein 1; [Cleaved into: Dynamin-like GTPase MGM1 large isoform; l-MGM1; Dynamin-like GTPase MGM1 small isoform; s-MGM1)] MGM1 MDM17 YOR211C YOR50-1; anti-MGM1 antibody
Ordering
Host
Rabbit
Reactivity
Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Protein A/G
Form/Format
Liquid
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH7.4
Applicable Applications for anti-MGM1 antibody
ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) MGM1 protein
Conjugation
Non-conjugate
Modification
Unmodified
Deliverables
1. 200ug recombinant immunogen protein/peptide (positive control).
2. 1mL preimmune serum (negative control)
3. 10mg rabbit polyclonal antibody purified by Protein A/G.
Quality Guarantee
1. Antibody purity >90% confirmed by SDS-PAGE.
2. Antibody titer > 1: 64,000 confirmed by ELISA
3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
Complementary Antibody
Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:
* 6*His Monoclonal Antibody #MBS1491670
* DYKDDDDK tag Monoclonal Antibody #MBS1493946
* GAPDH Monoclonal Antibody #MBS1495524
* GFP Monoclonal Antibody #MBS1496050
* Myc tag Monoclonal Antibody #MBS1497694
* GST Monoclonal Antibody #MBS1497871
* Sumo tag Monoclonal Antibody #MBS1498878
* Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510
* HA-Tag Monoclonal Antibody #MBS7135631
* E-Tag Monoclonal Antibody #MBS7135632
* TUBA1A Monoclonal Antibody #MBS7135645
* TUBB Monoclonal Antibody #MBS9018332
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
99,178 Da
NCBI Official Full Name
Mgm1p
NCBI Official Symbol
MGM1
NCBI Official Synonym Symbols
MNA1
NCBI Protein Information
Mgm1p
UniProt Protein Name
Dynamin-like GTPase MGM1, mitochondrial
Protein Family
UniProt Gene Name
MGM1
UniProt Synonym Gene Names
MDM17; l-MGM1; s-MGM1
UniProt Entry Name
MGM1_YEAST

Uniprot Description

Function: Dynamin-related GTPase required for mitochondrial fusion. Coordinates interaction between the inner and outer mitochondrial membrane to promote the formation of the double membrane. Ref.7 Ref.8 Ref.9 Ref.11

Subunit structure: Homooligomer. Associates with FZO1 through interaction with the intermembrane space domain of UGO1 which binds FZO1 through its cytoplasmic domain. Ref.8 Ref.9 Ref.13

Subcellular location: Dynamin-like GTPase MGM1 large isoform: Mitochondrion inner membrane; Single-pass type II membrane protein; Intermembrane side Ref.7 Ref.9 Ref.12. Dynamin-like GTPase MGM1 small isoform: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side Ref.7 Ref.9 Ref.12.

Post-translational modification: Cleavage of the transit peptide by mitochondrial processing protease (MPP) produces a long integral membrane form of MGM1 (l-MGM1). Further processing by the rhomboid protease PCP1 produces a short peripheral membrane form of MGM1 (s-MGM1). Both isoforms are required for full activity.

Miscellaneous: Deletion of MGM1 causes the mitochondria to fragment and aggregate, and subsequently to lose their mitochondrial DNA and become respiration deficient.

Sequence similarities: Belongs to the dynamin family.Contains 1 GED domain.

Sequence caution: The sequence CAA44637.1 differs from that shown. Reason: Frameshift at position 4. The sequence CAA63174.1 differs from that shown. Reason: Erroneous initiation. The sequence CAA99426.1 differs from that shown. Reason: Erroneous initiation. The sequence CAA99428.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on MGM1

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Product Notes

The MGM1 mgm1 (Catalog #AAA7155170) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) MGM1 Polyclonal Antibody reacts with Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) and may cross-react with other species as described in the data sheet. AAA Biotech's MGM1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), WB (Western Blot) (ensure identification of antigen). Researchers should empirically determine the suitability of the MGM1 mgm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MGM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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